Aortic stenosis classification

Abstract

The system (102) includes a digital information repository (104) configured to store an aortic valve area measurement, an average tranaortic pressure gradient measurement, and a peak aortic jet velocity measurement of a subject of interest. The system also includes a computing device (106). The computing device includes a memory (110) configured to store instructions (120) for an aortic stenosis classifier (122). The computing device further includes a processor (108) configured to execute stored instructions for the aortic stenosis classifier, the subject's severity of aortic stenosis is classified based at least on the subject's aortic valve area measurements, the average tranaortic pressure gradient measurements, and the peak aortic jet velocity measurements. The computing device also includes a display configured to display the severity.

Description

technical field

[0001] The following relates generally to classification, and more specifically to classification of aortic stenosis. Background technique

[0002] Aortic stenosis (AS) occurs in almost 10% of adults over the age of 80, with a 2-year mortality rate of approximately 50% unless outflow obstruction is relieved by aortic valve replacement, such as transcatheter aortic valve replacement (TAVR). ). The "AHA / ACC Guideline for the Management of Patients with Valvular Heart Disease" indicates a defined aortic valve area (AVA) <1.0 cm for severe AS 2 , Mean trans-aortic pressure gradient (MPG)>40mm Hg and peak aortic jet velocity (Vmax)>4m / s. This guideline has been used in intervention programs. Unfortunately, not all patients with severe AS meet the guidelines. Consequently, clinicians are sometimes in a gray area when diagnosing such patients, resulting in inconsistent assessments of AS severity and a lack of guidance on timing of intervention. Further...

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