Pharmaceutical use of Resina-Ferulae extract
A technology for extracts and medicaments, which is applied in the field of preparation of detoxification medicines from the extracts of traditional Chinese medicine aweishui, can solve the problems of drug dependence, side effects, poisoning and the like
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Embodiment 1
[0073] The Ferulicum extract of the present invention is used to prepare a drug for detoxification: Ferulic injection, which is prepared by conventional methods.
[0074] Ferulicum ferulae extract is prepared from Xinjiang ferulicum or Fukang ferulicum by the usual steam distillation method. Measured in parts by weight, take 0.1-20 parts of Xinjiang Ferulicum or Fukang Ferulicum, add 0.1-80 parts of purified water, carry out steam distillation, control the temperature at 105.5-108 ° C, collect 0.2-400 parts of the first distillate, and then Perform redistillation and collect 0.1 to 200 parts of the distillate, which is the Ferulicum extract. Ferulicum extract is a milky white liquid, a supersaturated solution of volatile oil, with a pH value of 4-5.7. Sent to the Analysis and Testing Center of the Chinese Academy of Sciences, and detected by GC-MS, it mainly contains: α-pinene, α-terpinene, 2-borneol, terpineol 4-ol, D-feulyl alcohol, pincarveol, β-ocimene A, B-ocimene B, di...
Embodiment 2
[0079] The Ferulicum extract of the present invention is used to prepare a drug for detoxification: Ferulic injection, which is prepared by conventional methods.
[0080] Ferulicum extract is prepared by the usual azeotropic distillation method. Take 1,000g of Xinjiang Ferulicum or Fukang Ferulicum, add 16,000ml of purified water, control the temperature at 105-108°C for azeotropic distillation, collect 8,000ml of the initial distillate, and then carry out redistillation. . Physicochemical property and main component of Ferulicum extract are identical with embodiment 1.
[0081] Add 5g of polysorbate 80 (for medicinal use) to 1000ml of Ferulicum extract, stir for 5min, add 7g of sodium chloride (for injection), then add water for injection to 1000ml, continue stirring for 5min, and pass through a micrometer of 0.22μm Membrane filtration, filling and sealing of 2ml ampoules, and sterilizing at 100°C for 30 minutes to obtain Ferulic Injection. Ferulic injection can be made in...
Embodiment 3
[0083] The ferulicum extract is used to prepare a kind of detoxification drug: the ferulic injection, which is prepared by a conventional method.
[0084] Ferulicum extract is prepared by the usual negative pressure distillation method. Take 500g of Xinjiang Ferulicum or Fukang Ferulicum, add 8000ml of purified water, control the conditions at 105-108°C / 1300-1400Pa, carry out negative pressure distillation, collect 4000ml of the initial distillate, and then carry out redistillation, and collect the redistillate that is Wei extract 1000ml. Physicochemical property and main component of Ferulicum extract are identical with embodiment 1.
[0085] Add 5g of polysorbate 80 (medicinal) to 1000ml of Ferulicum extract, stir for 5min, add 7g of sodium chloride (for injection), add water for injection to 1000ml, continue stirring for 5min, filter through 0.22μm micromembrane After that, fill and seal the ampoules, and sterilize at 100°C for 30 minutes to obtain Ferulic Injection. The...
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