Oral liquor for curing cerebral hemorrhage and its preparation method

A preparation method and oral liquid technology, which are applied to medical preparations containing active ingredients, pharmaceutical formulations, medical raw materials derived from leeches/helminths, etc. The effect of small damage and no toxic side effects

Inactive Publication Date: 2006-05-03
辽宁省血栓病中西医结合医疗中心
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

As for the hematoma itself, there is no way to treat it, we can only wait for natural absorption, and there is currently no effective drug to treat it

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] It is formulated from the following components (by weight):

[0044] Leech: Panax notoginseng: Rhubarb = 6:1:2

[0045] Take 300g of leech according to the above ratio and crush it into coarse powder, use 50% ethanol as solvent to impregnate for 24 hours, then percolate according to the law, collect 4500ml of filtrate at a flow rate of 2ml / min, concentrate under reduced pressure to 700ml, put to room temperature, centrifuge at 3000r / min, take The supernatant is ready for use; another 50g of Panax notoginseng and 100g of rhubarb are crushed into coarse powder, and 60% ethanol is added to reflux for extraction twice. The first time is 8 times the amount of solvent for 2.5 hours, the second time is 5 times the amount of solvent for 1.5 hours, combined with ethanol extraction liquid, recovered ethanol and concentrated to 3000ml, centrifuged at 3000r / min, the supernatant was combined with the leech liquid, left for 48 hours, refrigerated at 5°C, centrifuged at 3000r / min, the...

Embodiment 2

[0047] It is formulated from the following components (by weight):

[0048] Leech: Panax notoginseng: Rhubarb = 6:1:2

[0049] Take 900g of leech according to the above ratio and pulverize into coarse powder, use 80% ethanol as solvent to impregnate for 24 hours and percolate according to law, collect the filtrate 13500ml at a flow rate of 2ml / min, concentrate under reduced pressure to 2100ml, put to room temperature, and centrifuge at 3000r / min to take The supernatant is used for later use; another 150g of Panax notoginseng and 300g of rhubarb are crushed into a coarse powder, and 40% ethanol is added to reflux for extraction twice. The first time is 7 times the amount of solvent for 3 hours, the second time is 3 times the amount of solvent for 2 hours, combined with ethanol extraction liquid, recovered ethanol and concentrated to 900ml, centrifuged at 3000r / min, the supernatant and leech liquid were combined, placed for 48 hours, refrigerated at 10°C, centrifuged at 3000r / mi...

Embodiment 3

[0051] It is formulated from the following components (by weight):

[0052]Leech: Panax notoginseng: Rhubarb = 6:1:2

[0053] Take 1500g of leech according to the above ratio and grind it into coarse powder, soak it with 50% ethanol as solvent for 24 hours and percolate according to the law, collect the filtrate 67500ml at a flow rate of 2ml / min, concentrate it under reduced pressure to 3500ml, put it to room temperature, and centrifuge at 3000r / min. The supernatant is ready for use; take another 250g of Panax notoginseng and 500g of rhubarb and grind them into coarse powder, add 60% ethanol to reflux and extract twice, the first time is 11 times the amount of solvent for 2 hours, the second time is 7 times the amount of solvent for 1 hour, combined with ethanol extraction Liquid, recovered ethanol and concentrated to 1500ml, centrifuged at 3000r / min, the supernatant was combined with leech liquid, left for 48 hours, refrigerated at 2°C, centrifuged at 3000r / min to take the su...

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PUM

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Abstract

The invention relates to an oral liquid for treating cerebral hemorrhage prepared with leeches and a preparation method thereof, which is composed of the following components (in weight ratio): leeches: notoginseng: rhubarb = 6:1:2. The advantages of the wood invention are: scientifically screen drugs for the treatment of cerebral hemorrhage in modern medicine, its products have the function of promoting blood circulation and removing blood stasis, and promote the absorption of intracranial hematoma; it can advance the absorption time of hematoma, and the average daily blood absorption is obvious It is higher than those who do not take this medicine, and it has a very good effect on patients who enter the ventricle, especially for the acute stage of cerebral hemorrhage. It can reduce the mortality rate, and the total effective rate of treatment can reach 95%, so it has extremely important significance for the treatment of cerebral hemorrhage.

Description

[0001] Field [0002] The invention relates to a medicine for treating cerebral hemorrhage, in particular to an oral liquid for treating cerebral hemorrhage prepared by using leeches and a preparation method thereof. Background technique [0003] Cerebral hemorrhage is one of the frequently-occurring diseases recognized at home and abroad. Traditional Chinese methods generally use dehydrating agents to reduce intracranial pressure, nourish brain cells, and treat symptoms. As for the hematoma itself, there is no way to treat it, and we can only wait for natural absorption, and there is currently no drug with good curative effect to treat it. Contents of the invention [0004] The object of the present invention is to solve the above-mentioned problems, and provide a kind of oral liquid for treating cerebral hemorrhage prepared by using leeches and its preparation method. In order to fundamentally solve the problem of hematoma, promote the absorption of hematoma as soon as po...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/708A61P9/10A61K35/62
Inventor 姜典勋富春儒池明宇罗冬梅朱丹
Owner 辽宁省血栓病中西医结合医疗中心
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