The invention relates to an external detumescence and pain released wine for curing orthopedics disease. The invention is characterized in that the prescription consists of the following raw medicines by weight: 5 to 35 parts of dragon's blood, 15 to 35 parts of frankincense, 15 to 35 parts of myrrh,15 to 35 parts of safflower,15 to 35 parts of fresh szechuan lovage rhizome, 20 to 40 parts of common burreed rhizome, 15 to 35 parts of rhizoma zedoariae, 15 to 35 parts of angelica tail, 20 to 30 parts of fresh rhubarb, 20 to 40 parts of fresh pinellia tuber, 20 to 40 parts of fresh rhizoma arisaematis, 20 to 40 parts of nux vomica, 15 to 35 parts of amphor, 10 to 25 parts of manchurian wildginger, 30 to 40 parts of ephedra herb, 20 to 30 parts of fresh common monkshood mother root, 20 to 30 parts of fresh kusnezoff monkshood root, 30 to 45 parts of paniculate swallowwort root and 4000 to 5000 parts of alcohol with a concentration of 55 percent. The invention has the advantages that the invention has functions of promoting blood circulation, removing blood stasis, and relieving swelling and pain for obvious partial hematoma due to bones and muscles injury; and the invention is also used for curing diseases such as closed fracture, dislocation of joint, soft tissue injury, hypostasis and detumescence and pain. Besides, the invention also has the advantages of short treatment period, quick effect, low price and wide application, with a total effective rate of more than 90 percent.