Sea dog meat and bone meal capsule, preparation method and usage
A technology of sea dog meat and meat and bone meal, which is applied in the direction of pharmaceutical formulas, medical preparations containing active ingredients, active ingredients of aluminum/calcium/magnesium, etc., and can solve problems such as poor calcium supplementation effect
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Embodiment 1
[0049] This example relates to the pharmaceutical test of the sea dog meat and bone meal capsule of the present invention
[0050] 1. The toxicological safety evaluation test of the sea dog meat and bone meal capsule of the present invention
[0051] 1 Materials and methods
[0052] 1.1 Sample: Sea dog meat and bone meal capsules, brown powder, capsules. With its Seal Meat and Bone Powder Capsules, the acute toxicity test in mice, the micronucleus test in mouse bone marrow polychromatic erythrocytes, the sperm deformity test in mice, the Ames test, and the 30-day feeding test in rats were carried out.
[0053] 1.2 Experimental animals: Kunming mice, provided by the Laboratory Animal Department of China Medical University, approval number: Liaoshi Dongzhizi [2000] 015.
[0054] Wistar rats are provided by the Laboratory Animal Department of China Medical University, and the approval number is Liaoshi Dongzhizi [2000]015.
[0055] 1.3 Acute toxicity test in mice: 40 healthy Kunming ...
Embodiment 2
[0158] The raw materials of sea dog meat and bone meal capsules are: sea dog meat and bone meal, produced in Canada; calcium carbonate is natural calcium carbonate, produced from Zibo Schnauzer Industrial Co., Ltd.; empty capsules, produced from Boxing County Huifeng Gelatin Co., Ltd.
[0159] Mix 60% sea dog meat and bone meal with 40% weight percentage of calcium carbonate uniformly; then dry at 80°C for 12 hours, determine the moisture content to be 3.31%, grind, pass through a 100-mesh sieve, and pack into capsules to make product. Each capsule is 500mg, the recommended dosage is 3 times per person per day, 4 capsules each time, which is equivalent to 0.1g per kilogram of body weight (based on 60 kg of body weight).
Embodiment 3
[0161] The raw materials of sea dog meat and bone meal capsules are: sea dog meat and bone meal, produced in Canada; calcium carbonate is natural calcium carbonate, produced by Guilin Hongxing Chemical Industry Co., Ltd.; empty capsules, produced by Qinghai Gelatin Co., Ltd.
[0162] Mix 70% by weight sea dog meat and bone meal and 30% by weight calcium carbonate uniformly; then dry at 60°C for 10 hours, determine the moisture content to be 4.11%, grind, pass through a 120-mesh sieve, and put into capsules to make product. Each capsule is 500mg, the recommended dosage is 3 times per person per day, 4 capsules each time, which is equivalent to 0.1g per kilogram of body weight (based on 60 kg of body weight).
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