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Folium ginkgo injection and preparation thereof

A technology of ginkgo biloba and injection, which is applied in the field of ginkgo biloba large infusion and its preparation, and can solve the problems of irritation, inability to metabolize in patients with kidney disease, etc.

Inactive Publication Date: 2003-10-15
YANGTZE RIVER PHARM GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The use of sorbitol is not only irritating to a certain extent, but most patients with kidney disease cannot metabolize it, so its use has certain limitations
There is no use or report about the large infusion of Ginkgo biloba

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0017] Get 5000g of ginkgo biloba powder in 60% ethanol solution at 60-70°C temperature, warm soak for 3 hours, filter, add 7 times the amount of 60% ethanol solution, and warm soak for 2 hours at 60-70°C temperature, Filtrate, combine the filtrates, recover ethanol, concentrate to one-third of the original volume, add water to dilute to twice the original volume, stand for 24 hours, filter, the filtrate is adsorbed by the macroporous adsorption resin, and rinsed with distilled water until the effluent is clear , using 80% ethanol solution as a solvent, eluting, collecting the eluent, recovering ethanol, drying to dryness under reduced pressure, and refining to obtain Ginkgo biloba extract powder. Take Ginkgo biloba extract powder, add ethanol 100ml and water for injection 1000m, stir to dissolve, add povidone K30 to 440g and stir to dissolve, add 900g of sodium chloride and stir to dissolve, add water for injection to 8000ml, and use 0.1% sodium hydroxide Adjust the pH value ...

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PUM

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Abstract

The transfused gingko leaf liquid is prepared with the materials including gingko leaf, absolute alcohol, povidone K30, sodium chloride, antioxidant and injection water and no sorbierite. During itspreparation, gingko leaf extract is first extracted with gingko leaf and through hot soaking, filtering, column refining and other steps and then mixed with other materials. The transfused gingko leaf liquid can improve body's blood circulation, dilute coronary artery and cerebral artery and may be used in treating coronary heart disease, angina pectoris, cerebral thrombus, cerebral malfunction,ischemic cerebral apoplexy, etc. and improving the perception function of senile dementia and vascular dementia patients.

Description

technical field [0001] The invention relates to a ginkgo leaf infusion and a preparation method thereof. Background technique [0002] Ginkgo biloba is the dry leaf of Ginkgo biloba (Ginkgo biloba L.), a plant of the genus Ginkgo in the Ginkgo family. Ginkgo resources in my country account for about 70% of the world's total. In the past ten years, the medicinal value of Ginkgo biloba has been recognized by countries all over the world. At present, there are small needles, tablets, oral preparations, tinctures and other varieties in the domestic and foreign markets, among which the small needles produced by Schwabe in Germany are the most popular. And its Ginato small needle is prepared by ginkgo biloba, sorbitol and ethanol in a certain proportion. The use of sorbitol is not only irritating to a certain extent, but most patients with kidney disease cannot metabolize it, so its use has certain limitations. There is no use and report about the large infusion of Ginkgo bilob...

Claims

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Application Information

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IPC IPC(8): A61P7/02A61P9/10A61P25/28
Inventor 李旭东黄淑萍楼风昌欧亚华王东戴军平
Owner YANGTZE RIVER PHARM GRP CO LTD
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