Oral liquor for curing cerebral hemorrhage and its preparation method by using leach

A preparation method and oral liquid technology, applied in the field of drugs for the treatment of cerebral hemorrhage, can solve the problems of hematoma cannot be treated, and achieve the effect of advancing hematoma absorption time, definite drug effect, and reducing mortality

Inactive Publication Date: 2004-07-28
辽宁省血栓病中西医结合医疗中心
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

As for the hematoma itself, there is no way to treat it, we can only wait f

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] It is composed of the following components (by weight ratio):

[0044] Leech: Panax notoginseng: Rhubarb = 6:1:2

[0045] Take 300g leeches and crush them into coarse powder according to the above ratio. Follow the percolation method under flow extract and extract, immerse in 50% ethanol as a solvent for 24 hours and then percolate in accordance with the law. The flow rate is 2ml / min to collect 4500ml of leachate and reduce pressure. Concentrate to 700ml, put it to room temperature, centrifuge at 3000r / min, and take the supernatant for use; take another 50g of Panax notoginseng and 100g of rhubarb to crush into coarse powder, add 60% ethanol and reflux for extraction twice, the first time is 8 times the amount of solvent for 2.5 hours , The second time 5 times the amount of solvent for 1.5 hours, combine the ethanol extracts, recover the ethanol and concentrate to 3000ml, centrifuge at 3000r / min, combine the supernatant with the leech solution, store for 48 hours, refrigera...

Embodiment 2

[0047] It is composed of the following components (by weight ratio):

[0048] Leech: Panax notoginseng: Rhubarb = 6:1:2

[0049] Take 900g of leeches and crush them into coarse powder according to the above ratio. Follow the percolation method under flow extract and extract, immerse in 80% ethanol as a solvent for 24 hours and then percolate according to the law. The flow rate is 2ml / min to collect 13,500ml of leachate, and reduce pressure. Concentrate to 2100ml, put it to room temperature, centrifuge at 3000r / min, and take the supernatant for use; take another 150g of Panax notoginseng and 300g of rhubarb to crush into coarse powder, add 40% ethanol and reflux for extraction twice, the first time is 7 times the amount of solvent for 3 hours , The second 3 times the amount of solvent for 2 hours, combine the ethanol extracts, recover the ethanol and concentrate to 900ml, centrifuge at 3000r / min, combine the supernatant with the leech solution, store for 48 hours, refrigerate at 10...

Embodiment 3

[0051] It is composed of the following components (by weight ratio):

[0052] Leech: Panax notoginseng: Rhubarb = 6:1:2

[0053] Take 1500g of leeches and crush them into coarse powder according to the above ratio. Follow the percolation method under the item of fluid intrusion ointment and extract, immerse in 50% ethanol as a solvent for 24 hours and then percolate in accordance with the law at a flow rate of 2ml / min to collect 67500ml of leachate and reduce pressure. Concentrate to 3500ml, put it to room temperature, centrifuge at 3000r / min, and take the supernatant for use; another 250g of Panax notoginseng and 500g of rhubarb are crushed into coarse powder, and 60% ethanol is refluxed for extraction twice, the first time is 11 times the amount of solvent for 2 hours , The second time 7 times the amount of solvent for 1 hour, combine the ethanol extracts, recover the ethanol and concentrate to 1500ml, centrifuge at 3000r / min, combine the supernatant with the leech solution, stor...

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PUM

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Abstract

The present invention relates to an oral liquor for curing cerebral hemorrhage and its preparation method by using leech as main raw material. The oral liquor is made up by using the Chinese medicinal materials of leech, notoginseng and rhubarb according to the ratio of 6:1:2.

Description

[0001] Field [0002] The invention relates to a medicine for treating cerebral hemorrhage, in particular to an oral liquid for treating cerebral hemorrhage prepared by leech and a preparation method thereof. Background technique [0003] Cerebral hemorrhage is currently one of the multiple diseases recognized at home and abroad. Traditional Chinese methods generally use dehydrating agents to reduce intracranial pressure, nourish brain cells, and treat symptomatically. As for the hematoma itself, there is no cure, it can only wait for natural absorption, and there are currently no effective drugs for treatment. Summary of the invention [0004] The purpose of the present invention is to provide an oral liquid for treating cerebral hemorrhage prepared by leech and its preparation method in view of the above-mentioned existing problems. In order to fundamentally solve the problem of hematoma, promote the absorption of hematoma as soon as possible, and nourish the damage of healthy t...

Claims

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Application Information

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IPC IPC(8): A61P9/10
Inventor 姜典勋富春儒池明宇罗冬梅朱丹
Owner 辽宁省血栓病中西医结合医疗中心
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