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Chinese medicinal composition for treating irritable bowel syndrome and its preparation method

A technology for irritable bowel syndrome and composition, which is applied in the field of preparation of the traditional Chinese medicine compound composition, and can solve the problems of no kidney-tonifying effect, high price, and insignificant clinical application effect, etc.

Active Publication Date: 2005-08-17
GUIZHOU LIANSHENG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] To sum up, the drug combination in A has the duality of antidiarrheal and regulating constipation, focusing on regulating the pathogenesis, and its clinical application effect is not significant; The irritable syndrome is weak; the formula in C is to invigorate the spleen and relieve the liver, but has no effect on nourishing the kidney; the formula in group D has more than enough to strengthen the spleen, but not enough to nourish the kidney; the formula in group E is addictive after long-term use of poppy shell, and ginseng is a great tonic And the price is high, so it should be used with caution, the power of this prescription to invigorate the kidney is weak

Method used

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  • Chinese medicinal composition for treating irritable bowel syndrome and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0151] Take 150g gall, nutmeg (simmered) 150g, red ginseng 35g, antler cream 45g, ebony 150g, myrobalan meat (simmered) 150g, atractylodes 150g, tuckahoe 45g, woody incense 150g;

[0152] Among them, the red ginseng, Poria, and deer horn cream are crushed into fine powder; nutmeg, atractylodes, and woodsy are soaked in 10 times the amount of water for 2 hours, distilled for 5 hours, and the volatile oil is extracted, diluted with an equal volume of 95% ethanol, and added to 5 times the amount Include β-cyclodextrin (wet evenly with an appropriate amount of distilled water), make into granules, and dry naturally; soak the dregs after oil extraction with gall, ebony, and myrobalan meat with 8 times the amount of water for 0.5 hours, then decoct Three times, 1 hour each time, filter, concentrate the filtrate to a thick paste with a relative density of 1.35-1.38 (80°C), add fine powder of three flavors such as red ginseng, mix well, dry at 70°C, pulverize, granulate, and dry , mix...

Embodiment 2

[0154] Take 115g gall, nutmeg (simmered) 115g, red ginseng 20g, antler cream 40g, ebony 135g, myrobalan meat (simmered) 135g, atractylodes 135g, tuckahoe 40g, woody incense 135g.

[0155] Its preparation method is the same as that of Example 1.

Embodiment 3

[0157] Take gallnut 155g, nutmeg (simmered) 155g, red ginseng 40g, antler cream 52g, ebony 165g, myrobalan meat (simmered) 165g, atractylodes 165g, tuckahoe 52g, woody 165g.

[0158] The preparation method is the same as in Example 1.

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Abstract

The Chinese medicine composition for treating intestinal irritable syndrome is prepared with gallnut, nutmeg, red ginseng, deglued antler powder, dark plum and myrobalan fruit as material and through the technological process including water extraction, extracting volatile oil, inclusion with cyclodextrin, grinding into fine powder and other steps. The pharmacological experiments show that the medicine of the present invention can inhibit the motion of small intestine, resist the sthenic motion of small intestine caused by Neostigmine, resist diarrhea caused by rhubarb, promote the absorption of water inside intestine caused by mannitol, etc. and has relatively high anti-diarrhea effect and high safety.

Description

Technical field: [0001] The invention relates to a traditional Chinese medicine compound composition for treating irritable bowel syndrome, that is, a pharmaceutical composition prepared by using Chinese herbal medicine as a raw material, and also relates to a preparation method of the traditional Chinese medicine compound composition. Background technique: [0002] Irritable bowel syndrome (IBS) is a common non-organic intestinal disorder of the gastrointestinal tract with clinical features of chronic and recurrent attacks. Clinical symptoms are abdominal discomfort (abdominal pain, bloating) and abnormal bowel movements, such as changes in defecation habits (diarrhea or constipation), abnormal stools (loose, mucus, or hard stools), and increased frequency of defecation as the main manifestation, and persistent Existing or intermittent attacks, and pathological examinations are mostly without specific intestinal inflammatory lesions. At present, there is no effective treat...

Claims

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Application Information

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IPC IPC(8): A61K35/32A61K35/64A61P1/00A61P1/14
Inventor 孔繁智
Owner GUIZHOU LIANSHENG PHARMA
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