3 results about "Anti-diarrhea" patented technology

The application discloses a feed additive for improving intestinal health of animals and preventing and treating intestinal diseases and application thereof, and relates to the technical field of green and healthy breeding. The application firstly confirms that indole-3-butyric acid (IBA) has no toxic effect on cells and can relieve oxidative stress damage and inflammation damage of the cells in an effective concentration. Meanwhile, the application also fills the application blank of IBA as one of indole derivatives in livestock production, and provides experimental basis and theoretical basis for the fact that IBA is expected to be a new green additive for replacing antibiotics and zinc oxide. More importantly, the application also finds that IBA has positive effects in aspects of resisting diarrhea, repairing intestinal barrier damage, relieving intestinal inflammation and preventing and treating intestinal related diseases.

The application discloses a preparation method of humic acid anti-diarrhea medicine, and belongs to the technical field of biological medicine, which can greatly improve the anti-diarrhea activity intensity of humic acid substances by homogenizing and grading the humic acid substances, and the activity intensity of the prepared anti-diarrhea raw medicine can reach three times of that before grading; in addition, the original inactive samples can also show anti-diarrhea activity, so that the invalid humic acid resources obtain medicinal value. The method systematically realizes the efficient preparation of humic acid anti-diarrhea raw medicine, and has important practical significance and application value for enhancing the stability of the quality of the medicine raw material, expanding the selection range of the medicine raw material, improving the safety of the medicine raw material and solving the bottleneck problem in the actual production of pharmaceutical enterprises. Meanwhile, the system and operability of the whole method are strong, the applicability is high, and the method is easy to be applied in industrialization.

This invention belongs to the field of biotechnology, specifically relating to an antimicrobial peptide for improving intestinal health and combating diarrhea in animals, and its preparation method. The invention prepares a novel antimicrobial peptide with the amino acid sequence shown in SEQ ID NO:1. Experiments have verified that after one week of feeding in an unfamiliar environment, the antimicrobial peptide can slightly increase the levels of propionic acid and butyric acid in the experimental group of cats. Furthermore, the overall BCFAs levels in the experimental group were lower than those in the control group before and after transportation. Although there were no significant differences in α-diversity and β-diversity between the experimental group fed the antimicrobial peptide and the control group, feeding the antimicrobial peptide significantly increased the levels of Bacteroides, Parabacterium, and Prevotella in the experimental group, and significantly reduced the levels of harmful bacteria Salmonella and Actinomyces. Therefore, the antimicrobial peptide of this invention can be used to prepare products for improving intestinal health and combating diarrhea in animals, such as feed additives or oral liquids.