Medicine for treating neurasthenia
A neurasthenia and drug technology, applied in the field of medicine, can solve problems such as unfavorable treatment, patient dependence, and large side effects
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[0026] The preparation process of space mutagenesis strains to produce mannan peptides:
[0027] The mannan peptide produced by the space mutagenic strains of the present invention is prepared by the following method: preparation of space strains --- primary fermentation --- secondary fermentation --- fermentation liquid purification, and finally produce Mannan peptides.
[0028] Space strain preparation:
[0029] The α-hemolytic streptococcus carefully selected through space mutation breeding is used as the production strain.
[0030] A. Slant seed medium: 0.5% beef extract, 0.6% yeast extract, 0.5% peptone, 0.4% glucose, 0.5% sodium chloride, 3% agar, 8% sheep blood; pH7.4.
[0031] The slant seed medium is sterilized at a temperature of 121°C for 30 minutes and a steam pressure of 0.12Mpa.
[0032] Unseal the strain freezing tube, dilute it with sterile broth medium, insert it into the blood slant under aseptic conditions, and culture it at 38°C for 30 hours after inocul...
Embodiment 1
[0086] Example 1 Take 300g of the above-mentioned α-mannan peptide, 100g of fried jujube kernels, 50g of Radix Polygalae, 50g of Schisandra chinensis, 70g of Uncaria elata, 50g of Gastrodia elata, 60g of amber, 50g of Coptis chinensis, 90g of Albizia Julibrissin, 80g of Ganoderma lucidum, 50g of calamus, and Baiziren Divide 50g into 10 bags of medicine, first decoct the above traditional Chinese medicine three times, mix the decoction, mix α-mannan peptide with the decoction; gelatinize at 90-100°C for 20-30 minutes, gelatinize The final slurry is in the form of a transparent paste; spread the above paste evenly on the enamel plate, the thickness is as consistent as possible and as thin as possible, and then dried at 110°C for 45-60 minutes; the above dried material is crushed with a pulverizer, Sieve through a 60-mesh sieve and pack into 10g / bag.
[0087] The specific production process is produced according to the preparation process of granules in the 2000 edition of the Ph...
Embodiment 2
[0089] 1000g of the drug in Example 2 contains 300g of α-mannan peptide, 25g of fried jujube kernel, 20g of Radix Polygala, 25g of Schisandra chinensis, 25g of Uncaria elata, 25g of Gastrodia elata, 30g of amber, 25g of Coptis chinensis, 30g of Albizia jujuba, 30g of ganoderma lucidum, and calamus 25g, Baiziren 25g, Bupleurum 25g, Muxiang 20g, Chuanxiong 25g, Cyperus cyperi 35g, Citrus aurantium 20g, Tangerine peel 40g, Fried hawthorn 20g, Pueraria 15g, Tribulus terrestris 20g, Orange leaves 20g, Astragalus 10g, Codonopsis 10g, Licorice 20g, angelica 20g, raw land 15g, white peony 10g, ginseng 15g, atractylodes macrocephala 10g, polygala 10g, jujube kernel 15g, donkey-hide gelatin 10g, medlar 20g, amomum 10g.
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