Method of preparing active medicinal matter of lignin from broad-leaved tree and its use

A technology of lignin and active substances, which is used in the medical and pharmaceutical industry to accelerate healing and prevent the invasion of bacteria

Active Publication Date: 2006-03-01
溧阳常大技术转移中心有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

But there is no report as a drug for hemostasis, blood circulation, and bruises, such as US Patent Application 20040048804

Method used

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Experimental program
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Effect test

Embodiment Construction

[0012] 1. Preparation of lignin medicinal active substances

[0013] Poplar wood is used as raw material to prepare lignin-like active substances, which are extracted with water vapor in an alkaline environment. A batch of materials is continuously extracted within 12 hours until the pH is 14, and different fractions are cut according to the change of pH in different time periods. The fraction solutions prepared above are placed in the presence of polysaccharidase at room temperature for 2-18 months to degrade lignin units naturally, and the degradation solution ranges from pH 14 to pH 6. The degradation liquid is preliminarily separated by dialysis, reverse osmosis, ultrafiltration and other methods, and some substances with a molecular weight <4000 in the internal and external dialysate are extracted and added to the reactor, and nitric acid is added dropwise under stirring for extraction, and the insoluble Solid in water, i.e. lignin-polysaccharide complex active substance,...

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Abstract

The present invention relates to medicine industry, and is especially method of preparing lignin as active medicinal matter from broad-leaved tree and its use in treating acute soft tissue damage and skin damage. The present invention prepares lignin with poplar, birch and other broad-leaved tree material, and through the steps of water vapor extraction in alkaline environment to obtain fraction solution, naturally degrading at normal temperature in the presence of polysaccharidase for 2-18 months to obtain degraded liquid with pH lowered from 14 to 6, separating the degraded liquid to obtain active matter of molecular weight less than 4000, and sterilizing to obtain the medicine liquid for treating acute soft tissue damage and skin damage. The method liquid is applied to skin wound to reach astringency and inflammation-diminishing effects.

Description

technical field [0001] The invention relates to the medical and pharmaceutical industry, in particular to a method for preparing lignin medicinal active substances from broad-leaved trees and its use in treating acute soft tissue sprains and skin damage. Background technique [0002] Lignin is a kind of polymer with phenylpropane monomer as the skeleton and a network structure, and is one of the main components of plant cell walls. Due to different types of plants, different growth environment regions, and different extraction methods used, the molecular weight and molecular structure of lignin obtained are also different, resulting in different uses of lignin. At present, the application and research of lignin at home and abroad mainly lie in: 1. The direct concentration of lignin in papermaking waste liquid can be used as fuel. 2. Lignin products are mainly used in reports on mud water reducer, oil field drilling mud pour point depressant, rubber reinforcing agent, feed a...

Claims

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Application Information

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IPC IPC(8): A61K36/76A61K36/00A61P17/02
Inventor 张静
Owner 溧阳常大技术转移中心有限公司
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