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Pseudo-ginseng saponin oral disintegration tablet and preparing method

A technology of orally disintegrating tablets and Panax notoginseng saponins, which can be used in pharmaceutical formulations, medical preparations containing active ingredients, pill delivery, etc., can solve the problems of difficulty in taking medicine as required, pain of patients, inconvenient taking, etc. Easy to carry, guarantee the effect of treatment, and improve the effect of compliance

Active Publication Date: 2006-03-08
CHONGQING CONQUER PHARML
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Injections need to go to the hospital, which is inconvenient and bring pain to patients; tablets and capsules need to be swallowed with water, 2 tablets at a time, 3 times a day, for patients with dysphagia and those in places where water is inconvenient It is inconvenient for patients to take the medicine, and it is often difficult to take the medicine as required; in addition, the medicine usually needs to be taken for a long time, these factors may lead to poor compliance of the patient, so that the therapeutic effect cannot be guaranteed

Method used

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  • Pseudo-ginseng saponin oral disintegration tablet and preparing method
  • Pseudo-ginseng saponin oral disintegration tablet and preparing method
  • Pseudo-ginseng saponin oral disintegration tablet and preparing method

Examples

Experimental program
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Effect test

Embodiment 1

[0040] Embodiment 1: a kind of notoginseng saponin orally disintegrating tablet, it is made by notoginseng saponin 40, microcrystalline cellulose 15, mannitol 60, cross-linked polyvinylpyrrolidone 4, sodium carboxymethyl starch 6.5, all by weight Count of copies.

[0041] The specific preparation method: the above-mentioned components are dried, pulverized, sieved for pretreatment, then mixed evenly, and then directly compressed into tablets to obtain the orally disintegrating tablets of notoginseng saponins.

Embodiment 2

[0042] Embodiment 2: a kind of notoginseng saponin orally disintegrating tablet, it is composed of notoginsenoside 20, microcrystalline cellulose 15, mannitol 45, cross-linked polyvinylpyrrolidone 2, carboxymethyl starch sodium 8, sodium bicarbonate 3.5, Citric acid 2, glycyrrhizin 4, aspartame 10, orange essence 8, and polyethylene glycol 6000 are made into 2, all in parts by weight.

[0043] The specific preparation method: after drying, pulverizing, sieving and other pretreatments of the above components, the notoginseng saponin orally disintegrating tablet is prepared by the powder direct compression method.

Embodiment 3

[0044] Example 3: A notoginsenoside orally disintegrating tablet, which is made of notoginsenoside 50, microcrystalline cellulose 30, mannitol 30, low-substituted hydroxypropyl cellulose 12, glycyrrhizin 18, and strawberry essence 16 , all in parts by weight.

[0045] The specific preparation method is as follows: the above-mentioned components are pretreated by drying, pulverizing and sieving, and the notoginseng saponin orally disintegrating tablet is prepared by a freeze-drying method.

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Abstract

The present invention relates to an arasaponin oral disintegrant tablet and its preparation method. Its composition includes (by weight portion) 2-60 portions of arasaponin, 1-20 portions of disintegrant and 2-100 portions of filling agent.

Description

technical field [0001] The invention relates to a notoginseng saponin tablet and a preparation method thereof, in particular to a notoginseng saponin tablet which has the functions of promoting blood circulation and removing blood stasis, dredging channels and collaterals, inhibiting platelet aggregation and increasing cerebral blood flow, and is used for cerebral road stasis, apoplexy and hemiplegia, Oral disintegrating tablets of notoginseng saponins for patients with symptoms such as heart stasis, chest obstruction and heart pain, sequelae of cerebrovascular disease, angina pectoris of coronary heart disease and its preparation method. Background technique [0002] Panax notoginsenoside is the active ingredient extracted from the reed head of Panax notoginseng, an Araliaceae plant, according to a certain process. It has the effects of promoting blood circulation and removing blood stasis, dredging channels and activating collaterals, inhibiting platelet aggregation and in...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/704A61K9/20A61P7/02A61P9/10
Inventor 王从芬陈艳秋
Owner CHONGQING CONQUER PHARML
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