Method for extracting simultaneously general alkaloid and starch from fritillary

Abstract

The invnetion discloses a method to separate and extract synchronously total alkaloid and starch from caladium, which comprises: adding the caladium powder into alcohol, heating to reflux extract, hypersonic extract or quench extract, condensing the obtained material; recycling alcohol to obtain and dissolve the extract in chlorhydric acid; filtering, extracting the acid liquid with petroleum ether and ethyl acetate, alkalizing with ammonia to make the pH value larger than 9; extracting with chloroform till supernatant has no color, recycling chloroform and obtaining total alkaloid; drying and breaking the residual. floating on NaOH or NaHSO3 solution of the fine powder; abandoning the supernatant; using distilled water repeatedly to suspense the deposition; abandoning the supernatant, centrifugalizing the liquid, abandoning supernatant and impurity in bottom of liquid, and obtaining pure product. This invention is simple with high yield.

Description

Technical field:

[0001] The invention discloses a method for simultaneously separating and extracting total alkaloids and starch from Fritillaria japonicus, belonging to the technical field of separating and extracting chemical components of traditional Chinese medicine. Background technique:

[0002] Fritillaria is the dried bulb of Fritillaria, a medicinal plant of the genus Fritillaria, containing alkaloids, saponins, terpenes, steroids, fatty acids, purines, pyrimidines and other compounds. The content in dried bulbs can reach 8%. These substances have multiple effects such as clearing away heat and moistening the lungs, relieving cough and eliminating phlegm. It is a commonly used traditional Chinese medicine for relieving cough and reducing phlegm. In addition, the dried bulbs of Fritillaria also contain more starch, and the total biomass of the dried Fritillaria bulbs is 40-60%. For traditional Chinese medicine chemists and plant chemists, they are concerned with t...