Naoxinqing Chinese medicine dispersible tablet and its preparing process

A preparation process and technology of dispersible tablets, applied in the field of Naoxinqing dispersible tablets and its preparation, can solve the problem of incomplete preparation process of original Naoxinqing tablets, lack of ethyl acetate dosage, relative density of medicine solution during extraction time, and influence on extraction effect And other issues

Inactive Publication Date: 2006-08-09
福寿堂制药有限公司 +1
View PDF0 Cites 7 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, the preparation process of Yuannaoxinqing Tablets is not complete enough. During the water extraction process of dried persimmon leaves, there is no explanation for the amount of water added, and the original extraction process lacks the amount of ethyl acetate, the extraction time and the relative density of the medicinal solution before extraction, which affects Important Factors for Extraction Effects

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Naoxinqing Chinese medicine dispersible tablet and its preparing process
  • Naoxinqing Chinese medicine dispersible tablet and its preparing process
  • Naoxinqing Chinese medicine dispersible tablet and its preparing process

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0103] Take dried persimmon leaves, add water to decoct twice, add 14 times the amount of water for the first time, decoct for 2 hours, add 12 times the amount of water for the second time, decoct for 1 hour, combine the decoction, filter, and the filtrate is at a temperature of 60-65°C , concentrated under reduced pressure to a relative density of 1.12 to 1.15 (measured at 60°C) under a vacuum of 0.06-0.08Mpa, add ethanol to make the alcohol content 85%, let it stand overnight, and filter the supernatant for subsequent use; Wash twice with 65% ethanol, the amount is 3 times of the precipitation, stir for 30 minutes, collect the washing liquid, let it stand, absorb the supernatant and combine with the previous supernatant, recycle the ethanol, add water to dissolve the obtained extract, add water to the obtained extract Dissolve to a relative density of 1.10 and filter. The filtrate was extracted four times with ethyl acetate, and the amount each time was 4 times the amount of...

Embodiment 2

[0105] 45 grams of dried persimmon leaf extract, 220 grams of microcrystalline cellulose, 65 grams of crospovidone, and 1.8 grams of magnesium stearate. Other steps are the same as in Example 1.

Embodiment 3

[0107] 55 grams of dried persimmon leaf extract, 230 grams of microcrystalline cellulose, 75 grams of crospovidone, and 2.2 grams of magnesium stearate. Other steps are the same as in Example 1.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The present invention relates to a Chinese medicine Naoxinqing dispersing tablet and its preparation process. It is made up by using (by weight portion) 45-55 portions of dried persimmon leaf extract, 220-230 portions of microcrystalline cellulose, 65-75 portions of cross-linked povidone and 1.8-2.2 portions of magnesium stearate through a certain preparation process. Said preparation process includes the following several main steps: decocting persimmon leaf at twice, combining decoctions, filtering, concentrating, adding ethyl alcohol, precipitating, drying to obtain dried extract, adding microcrystalline cellulose, cross-linked povidone and magnesium stearte, pulverizing, granulating and tableting to obtain said product.

Description

technical field [0001] The invention relates to a Naoxinqing dispersible tablet and a preparation process thereof. Background technique [0002] Coronary heart disease and angina disease are clinically common and frequently-occurring diseases, and the morbidity and mortality rates tend to increase in recent years. Coronary heart disease and angina pectoris belong to the category of thoracic obstruction in traditional Chinese medicine. Chinese medicine believes that: its cause lies in blood stasis, its main disease lies in the heart, and its cure lies in circulation. Naoxinqing Tablet is a pure traditional Chinese medicine preparation refined from persimmon leaves and its effective parts. Naoxinqing tablet has the effects of promoting blood circulation and removing blood stasis, dredging collaterals and relieving pain, and calming the nerves. It can increase coronary blood flow, dilate blood vessels, and improve myocardial ischemia. It has a good therapeutic effect on coro...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/44A61K9/20A61P9/10
Inventor 胡起玮
Owner 福寿堂制药有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap