Tanshinone I derivatives and pharmaceutical application thereof
A derivative, the technology of tanshinone, applied in the field of medicine, can solve the problems that the molecular structure is difficult to modify, and the medicinal value of tanshinone I has not been fully developed, so as to improve bioavailability, bioavailability and curative effect, and biological Effect of Utilization and Enhancement of Efficacy
CN1837200AInactive Publication Date: 2006-09-27秦引林
Patent Information
- Authority / Receiving Office
- CN · China
- Current Assignee / Owner
- 秦引林
- Publication Date
- 2006-09-27
- Estimated Expiration
- Not applicable · inactive patent
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Abstract
The invention discloses a tanshinoneIderivant and application in pharmacy, which is characterized by the following: the derivant constitutional formula is showed in the right chart: when R1 represents -Ar, R2,R3 represents hydrogen or alkyl with one to eight carbon atoms, cycloalkyl, aromatic nucleus or heterocyclic radical; or R2-N-R3 represents nitrogen saturation aza with nitrogen, imidazoline and its derivant, glyoxaline and its derivant, diethylenediamine and its derivant, piperidine and its derivant, morpholine and its derivant; when R1 represents -H, R2, R3 represents hydrogen and alkyl with three to eight carbon atoms, cycloalkyl, aromatic nucleus; or R2-N-R3 represents cyclohexylamine, imidazoline and its derivant, glyoxaline and its derivant, diethylenediamine derivant, piperidine derivant, morpholine derivant. The derivant can apply for preparing clinical preparation.
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Claims
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