45 results about "Diethylenediamine" patented technology

The invention discloses a tanshinoneIderivant and application in pharmacy, which is characterized by the following: the derivant constitutional formula is showed in the right chart: when R1 represents -Ar, R2,R3 represents hydrogen or alkyl with one to eight carbon atoms, cycloalkyl, aromatic nucleus or heterocyclic radical; or R2-N-R3 represents nitrogen saturation aza with nitrogen, imidazoline and its derivant, glyoxaline and its derivant, diethylenediamine and its derivant, piperidine and its derivant, morpholine and its derivant; when R1 represents -H, R2, R3 represents hydrogen and alkyl with three to eight carbon atoms, cycloalkyl, aromatic nucleus; or R2-N-R3 represents cyclohexylamine, imidazoline and its derivant, glyoxaline and its derivant, diethylenediamine derivant, piperidine derivant, morpholine derivant. The derivant can apply for preparing clinical preparation.

A polishing composition for semiconductor wafer polishing comprising, colloidal silica prepared from an active silicic acid aqueous solution obtained by removal of alkali from alkali silicate and at least one nitrogen containing basic compound selected from a group consisting of ethylenediamine, diethylenediamine, imidazole, methylimidazole, piperidine, morpholine, arginine, and hydrazine, wherein pH of the colloidal silica is of 8.5 to 11.0 at 25° C. by containing quaternary ammonium hydroxide.

The invention discloses a method for producing high-purity triethylene diamine, which comprises the following steps: using a triethylene diamine reaction liquid from which low boiling point substances (including ammonia gas, water, ethylene diamine, diethylenediamine and the like) are removed as a raw material for rectification, adding C2-C5 hydroxylamine compounds which contain branched chains (methyl or ethyl groups) or contain no branched chains and account for 40-120% of the weight of the triethylene diamine reaction liquid, and rectifying on a rectifying tower to obtain a high-purity triethylene diamine solution, wherein the obtained azeotropic solution can be directly used as a catalyst, the concentration of the solution can be changed as required by regulating vacuum pressure, and the solution can be subject to cooling crystallization to separate out triethylene diamine the purity of which is higher than 99.9%. The invention has the characteristics of simple operating process and high purity of the purified product.

The invention discloses a tanshinone IIA derivant and application in pharmacy, which is characterized by the following: the derivant constitutional formula is showed in the right chart; when R1 represents -Ar, R2,R3 represents hydrogen or alkyl with one to eight carbon atoms; or R2-N-R3 represents saturated heterocycle with nitrogen, imidazoline and its derivant, glyoxaline and its derivant, diethylenediamine and its derivant, piperidine and its derivant, morpholine and its derivant; when R1 represents -H, R2,R3 represents alkyl with three to eight carbon atoms, cycloalkyl and aromatic nucleus; or R2-N-R3 represents cyclohexylamine, imidazoline and its derivant, glyoxaline and its derivant, piperazine, piperazine and derivant of derivant. The derivant can improve the bioavailability of original chemical compoundm.

The invention belongs to the technical field of chemical synthesis and relates to a preparation method of N,N-diethylenediamine. The preparation method of the N,N-diethylenediamine comprises the following steps: (1) preparing 2-diethylamine-based chloroethane hydrochloride: performing heat-preserving reaction on a chlorinating agent and diethylamine ethanol in a reaction solvent, concentrating a reaction solvent after the heat-preserving reaction, adding low molecular alcohol or ester after concentrating, performing recrystallization to obtain a 2-2-diethylamine-based chloroethane hydrochloride wet product and drying to obtain a 2-diethylamine-based chloroethane hydrochloride dry product; (2) preparing the N,N-diethylenediamine: performing heat-preserving and pressure-maintaining reactionon the 2-diethylamine-based chloroethane hydrochloride and excessive liquid ammonia for more than or equal to 4 hours under the conditions that the pressure is 0 to 10 MPa and the temperature is 10 to100 DEG C, recycling the residual ammonia gas after the reaction, adding alkali into the reaction liquid, performing cooling alkali analysis, separating out the lower layer of alkaline liquid, rectifying an organic layer and collecting the fraction with the temperature of 143 to 148 DEG C, to obtain the N,N-diethylenediamine. The N,N-diethylenediamine prepared according to the method provided bythe invention has the advantages of high yield, high content, simplicity in operation, low raw material cost and the like.

The invention provides a method for synthesizing 4,4'-diphenic acid. In the method, high-boiling-point polyethylene glycol 400 is used as a solvent, cuprous iodide (CuI) is used as a catalyst, and 4,4'-diphenic acid is obtained in the condition of presence of diethylenediamine and potassium hydroxide (KOH) by a reduction coupling new method. The synthesis method has the advantages that the method for synthesizing 4,4'-diphenic acid is simple, the synthesizing condition requirements are not high, the operation is easy, the production cost is low, the yield is very high, the purity is also very high and the repeatability is good, so that the method is suitable for the requirements of large-scale industrialized production; the solvent polyethylene glycol 400 used by the reaction system has high steam pressure, does not pollute the environment and is environment-friendly; and the purification method is simple, column separation purification is not needed, and purification can be carried out just by a common recrystallization method.

The invention discloses polyurethane integral skin foam and a preparation method thereof, and relates to the field of high polymer materials. The foam is prepared from a material A and a material B according to the weight ratio of 5 to 2-3, wherein the material B is modified MDI; the material A is prepared from the following raw materials in parts by weight: 70 to 80 parts of polyether polyol, 0.5to 2 parts of a hole opening agent, 0.5 to 1.5 parts of a foam stabilizing agent, 1 to 5 parts of a silicone surfactant, 1 to 5 parts of A-1, 1 to 5 parts of a PC-77 catalyst, 1 to 3 parts of diethylenediamine, 2 to 8 parts of ethylene glycol, 1 to 5 parts of an A33 catalyst and 0.5 to 1.5 parts of water. According to the application, water serves as a foaming agent completely and does not contain Freon which damages the atmospheric ozone layer; the polyurethane integral skin foam has high elastic resilience, wear resistance and impact resistance when the polyurethane integral skin foam is used for an automobile steering wheel, and further has the advantages of low odour, environmental friendliness, pollution free and the like, and can reach the hardness of 58 to 68 (shore A), the resilience of greater than or equal to 50 percent, the odour (23 DEG C) of level 1.4, the odour (40 DEG C) of level 2.0, the odour (80 DEG C) of level 2.5, and the VOC value of less than or equal to 55 mu g/m<3>.

This invention belongin to medicinal chemistry, pubilize the structure and synthesis of aryl-diethylenediamine modified benzo[b]thiophenes with antidepressant function. Its structure is depicted as picuture. Ar structure is as depicted.the synthesis of the compound is as followings: mix 1M 3-propionyl benzo[b]thiophenes,1-5M cavaform and 1-5M aryl-piperazidine hydrochlorate in 1-50 weight folds ethanol, inverse flowing react 1-80 hours, obtain 1-( benzo[b]thiophenes-3)-2- methyl-3-( 4-aryl-piperazidine-)1- acetone; Mix 1M 1-( benzo[b]thiophenes-3)-2- methyl-3-( 4-aryl-piperazidine-)1- acetone and 0.2-5M sodium borohydride in 1-50 weight folds of ethanol, react at 0-100deg C for 1-20, 1-( benzo[b]thiophenes-3)-2- methyl-3-( 4-aryl-piperazidine-)1- propanol obtained. This kind of compounds could be used for antidepressant drug preparation in the form of free alkali or salt. This invention is advantageous in simplied preparation and easy manipulation.

The invention relates to a fluorescence sensing material based on rhodamine B and hydroxy-4-biphenylcarbonitrile, and a preparation method and application thereof, and belongs to the technical fieldsof a fluorescence chemical sensing material and chemical analysis and detection. The preparation method comprises the following steps: dissolving rhodamine diethylenediamine and 3-formyl-4-hydroxy-4-biphenylcarbonitrile into absolute ethanol, adding a proper amount of glacial acetic acid, stirring and refluxing in an oil bath pot, cooling to room temperature after the reaction, reducing pressure and removing the solvent to obtain a crude product, and performing recrystallization in ethanol to obtain the fluorescence sensing material. The fluorescence sensing material prepared by the method hasmultiple responsiveness on four metal ions such as Zn<2+>, Al<3+>, Fe<3+> and Cr<3+>, can realize effective detection on the trace amount of the target metal ions in the environment water sample wellby taking out different fluorescence signals, and has the characteristics of easily available raw materials, simple preparation process, high product stability, high detection sensitivity and the like.

The invention provides a kind of super soft epoxy curing agent, which comprises the chemical reaction of combination with four chemicals of diethylenediamine, propylene carbonate, oleic acid, and castor oil. The curing agent is blended into super soft epoxy adhesive with epoxy resin and epoxy diluent. Finally, the super soft epoxy adhesive is used in the application of cloth cover, or widely used in bonding repair, house wall decoration and so on.

The invention discloses an epoxy drawn grain anticorrosive floor. The epoxy drawn grain anticorrosive floor comprises a component A and a component B, wherein the component A comprises 40-50 parts of epoxy bisphenol A type epoxy resin, 30-40 parts of phenolic aldehyde type resin, 0.1-0.6 part of dicyclohexylmethane diisocyanate, 5-8 parts of cyclohexane, 1-3 parts of n-butyl alcohol, 0.1-0.4 part of butenoic acid, 0.8-0.9 part of cobalt naphthenate, 1.0-1.8 parts of wetting dispersant, 0.8-1.0 part of a levelling agent, 0.5-0.7 part of a defoaming agent, 10-16 parts of diatomite and 5-10 parts of mica powder; the component B comprises 10-15 parts of tertiary butyl styrene, 8-15 parts of styrene, 3-6 parts of diethylene diamine and 0.5-1.0 part of toluenesulfonic acid; and ratio of the component A to the component B in part by weight is 10:3. The obtained epoxy drawn grain anticorrosive floor has the advantages of no seam, good resistance to chemical reagents, corrosion resistance, dust prevention, convenience in maintenance, low maintenance cost and beautiful appearance and is especially outstanding in corrosion resistance, skid resistance and flexibility.

The present invention provides micro-electronics special used chelating agent uses method for effectively removing metal ion on base material surface. It contains adding 0.1-3 per cent micro-electronics special chelating agent diethylenediamine tetraacetic acid tetrahydroxy ethyl ethylene diamine in usual polishing solution by volume, if polishing solution being basicity then polishing; if polishing solution being acidity then adding 1-5 per cent oxyful in above-mentioned polishing solution then polishing; putting above-mentioned polished section in purge tank and adding 0.1-3 per cent micro-electronics special chelating agent diethylenediamine tetraacetic acid tetrahydroxy ethyl ethylene diamine in cleaning agent by volume percentage, and 1-5 per cent oxyful, then to make cleaning. The present invention can oxidize metal atom existing chip surface to metal ion and fully chelating with chelating agent, thereby to obtain removing.

The invention discloses a preparation method of a high-efficiency solidified water-resistant adhesive. The method comprises the following steps: 1) preparing a raw material of hydrogenated bisphenol type A epoxy resin, then preparing the hydrogenated bisphenol type A epoxy resin for standby; 2) performing modification on the hydrogenated bisphenol type A epoxy resin, adding a modifier and performing a heating reaction with the hydrogenated bisphenol type A epoxy resin to obtain the modified epoxy resin; 3) preparing a mixed curing agent, wherein the mixed curing agent comprises 20-45 pars of a cyanoethylated diethylenediamine curing agent, 6-12 parts of ethylene glycol diglycidylether, 15-30 parts of a filling material, 9-15 parts of an acrylic acid ester rubber, and 7-20 parts of dimethyl methylphosphate.; and 4) independently packaging the modified epoxy resin and the mixed curing agent, and packaging the every two materials. Through reasonable control the ratio between the reactants, the reaction condition can be controlled in a reasonable mode, and the epoxy resin adhesive with high endurance is prepared.

The invention discloses a preparation method of a chemical disinfectant. The preparation method is characterized by comprising the following steps that (1) 0.3 to 1.5 percent of bromized diethylenediamine and 0.12 to 0.35 percent of ciprofloxacin are added into 100ml of sterile water; heating is performed to be about 40 DEG C; stirring is performed until a clear solution is obtained; (2) 0.2 to 1.7 percent of lauryl sodium sulfate, 2 to 15 percent of ethyl alcohol and 4 to 10 percent of glycerine for medical purposes are added into 100ml of sterile water; stirring is performed at 20 to 25 DEG C until a clear solution is obtained; (3) the mixture in the step (1) and the mixture in the step (2) are mixed; water is added for reaching the total content of 100 percent; the mixture is uniformly stirred at 20 to 25 DEG C to obtain a finished product. The preparation method has the advantages that the sterilization effect of the prepared disinfectant is good; the sterilization lasting for a long time is realized; no stimulation is caused on the human body.

The invention discloses an o-vanillin diethylenediamine vanadium coordination compound, and a synthesis method and the application thereof. The chemical formula of the o-vanillin diethylenediamine vanadium coordination compound is {[VOL*(H2O)]*H2O}n and the molecular formula is C18H22N2O7V; the ligand of the o-vanillin diethylenediamine vanadium coordination compound is o-vanillin diethylenediamine. The VOSO4 and the o-vanillin diethylenediamine serving as the ligand are subjected to reaction by a hydrothermal method, and the ligand and metal ions are subjected to coordination, so that the brand new o-vanillin diethylenediamine vanadium coordination compound is obtained. The coordination compound is expected to be applied in the fields of oxidation resistance, cancer resistance and the like. The synthesis method provided by the invention is simple, convenient, safe, mild in reaction condition, high in yield, high in purity and favorable for subsequent tests.

The invention relates to the pharmaceutical use of (1'-(7''-chlorine-quinoline-4''-radix) piperazine-4'-radix)-3-monoprop. The (1'-(7''-chlorine-quinoline-4''-radix) piperazine-4'-radix)-3-monoprop is a product of the metabolism of human body, which can inhibit the growth of malaria parasites and the fission of the schizont thereof, and can be used for the preparation of anti-malarial drugs.

The invention discloses a high-efficiency solidified water-resistant adhesive. The high-efficiency solidified water-resistant adhesive comprises the following components in parts by weight: 150-270 parts of a hydrogenation bisphenol type A epoxy resin base-material, 20-45 pars of a cyanoethylated diethylenediamine curing agent, 6-12 parts of ethylene glycol diglycidylether, 15-30 parts of a filling material, 9-15 parts of an acrylic acid ester rubber, and 7-20 parts of dimethyl methylphosphate. By reasonable control of ratio between the reactants, the reaction condition can be controlled in a reasonable mode, and the epoxy resin adhesive with high endurance is prepared. The epoxy resin adhesive has the excellent moisture resistance and heat resistance, excellent machinery characteristics such as impact resistance, and has good bonding performance and, endurance performance, and a preparation method is simple and easy to operate.

The invention provides a water-soluble sarafloxacin hydrochloride granule and a preparation method thereof. The invention aims to solve the technical problems that an existing sarafloxacin hydrochloride medicine is poor in treatment effect and serious in medicine residues. The water-soluble sarafloxacin hydrochloride granule is prepared from the following raw materials in parts by weight: 15-45 parts of diethylene diamine, 150-220 parts of a cyclodextrin-methyl vinyl ether/maleic anhydride copolymer, 100 parts of sarafloxacin hydrochloride, 635-735 parts of anhydrous dextrose and a proper amount of water. The preparation method comprises the following steps: respectively weighing the diethylene diamine and the cyclodextrin-methyl vinyl ether/maleic anhydride copolymer, adding the diethylene diamine and the cyclodextrin-methyl vinyl ether/maleic anhydride copolymer into hot water, and carrying out uniform mixing to obtain a mixture I; respectively weighing sarafloxacin hydrochloride and anhydrous dextrose, and carrying out uniform mixing to obtain a mixture II; putting the mixture II into a three-dimensional fluidized bed, and carrying out fluidized-bed granulation by taking the mixture I as an adhesive; and controlling air inlet temperature and the like during the granulation so as to finally obtain sarafloxacin hydrochloride particles. The water-soluble sarafloxacin hydrochloride granule provided by the invention can be widely applied to the technical field of veterinary drugs.

The invention relates to a preparation method of hydroxypropyl diethylenediamine taking piperazine and epoxy chloropropane as raw materials. (The formal is shown in the description.).