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results about "Sarafloxacin" patented technology
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Sarafloxacin (INN) is a quinolone antibiotic drug, which was removed from clinical use by its manufacturer Abbott Laboratories from April 30, 2001.
A soluble solid preparation of sarafloxacin hydrochloride and a method for preparing the same
Pending
CN122272588A
Sucrose
Livestock
This invention provides a soluble
solid
dosage form
of
sarafloxacin
hydrochloride
and its preparation method, belonging to the field of
pharmaceutical technology
. The soluble
solid
dosage form
of
sarafloxacin
hydrochloride
of this invention comprises the following components in parts by weight: 10 parts
sarafloxacin
hydrochloride
, 6-15 parts soluble
phosphate
, 2-10 parts stabilizer, and 65-82 parts
diluent
; wherein the stabilizer is tetrasodium ethylenediaminetetraacetate or
ethylenediaminetetraacetic acid
; and the
diluent
is at least one selected from
anhydrous
glucose,
sucrose
,
lactose
, and
maltodextrin
. The soluble
solid
dosage form
of sarafloxacin hydrochloride of this invention has good water
solubility
; even at high concentrations (5000 ppm), the solution remains relatively clear, making it less likely to
cause blockage
of drinking water pipelines when administered to
livestock
farms; furthermore, it is suitable for preparing solutions with different water qualities, and no special requirements are needed for
water quality
during clinical use.
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Owner:
ZHEJIANG NEXCHEM PHARMA
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Dextrin
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Medicinal chemistry
Maltodextrin
Ethylenediaminetetraacetic acid