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1 results about "Sarafloxacin" patented technology

Sarafloxacin (INN) is a quinolone antibiotic drug, which was removed from clinical use by its manufacturer Abbott Laboratories from April 30, 2001.

A soluble solid preparation of sarafloxacin hydrochloride and a method for preparing the same

PendingCN122272588ASucroseLivestock
This invention provides a soluble solid dosage form of sarafloxacin hydrochloride and its preparation method, belonging to the field of pharmaceutical technology. The soluble solid dosage form of sarafloxacin hydrochloride of this invention comprises the following components in parts by weight: 10 parts sarafloxacin hydrochloride, 6-15 parts soluble phosphate, 2-10 parts stabilizer, and 65-82 parts diluent; wherein the stabilizer is tetrasodium ethylenediaminetetraacetate or ethylenediaminetetraacetic acid; and the diluent is at least one selected from anhydrous glucose, sucrose, lactose, and maltodextrin. The soluble solid dosage form of sarafloxacin hydrochloride of this invention has good water solubility; even at high concentrations (5000 ppm), the solution remains relatively clear, making it less likely to cause blockage of drinking water pipelines when administered to livestock farms; furthermore, it is suitable for preparing solutions with different water qualities, and no special requirements are needed for water quality during clinical use.
Owner:ZHEJIANG NEXCHEM PHARMA +1