Gel for removing ocular by ice pearl and its preparation

A technology for ophthalmic gels and preparations, which is applied in the field of Bingzhen Quyi eye gel preparations and its preparation, which can solve the problems of short drug retention time, small drug absorption, and influence on drug efficacy, so as to prolong the drug action time , the frequency of medication is less, and the effect of increasing the curative effect of the drug

Active Publication Date: 2007-01-17
湖北远大天天明制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

This patented product helps improve vision for patients who are prescribed an opaque solution or surgery that damages their crystalline lenses due to diseases such as diabetes mellitus (DM). It contains certain ingredients like vitamins B1, D2, E, CN, L-arginine hydrochloride, glycerol stearinate sodium salt, chondroitin sulfates, lycopene-4 serving as well as others which help protect against damage from light exposure during procedures. These products make up one part of this new formulation called OC) while still being able to provide some benefits over regular solutions without causing discomfort or side effects on ocular tissues.

Problems solved by technology

This patented technical problem addressed in this patent relates to finding an effective solution for controlling ocular disease without causing side effects like medications used alone (such as sterile injection).

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Pearl layer powder 350g

[0032] Zinc gluconate 4.18g

[0033] β-carotene 0.003g

[0034] Vitamin E 1g

[0035] borneol 0.6g

[0036] Carbomer 941 10g

[0037] Tween 80 2g

[0038] Benzalkonium Chloride 1g

[0039] Borax 3g

[0040] Glycerol 15.5g

[0041] Add water for injection to 1000ml

[0042]Add pearl layer powder with water for injection, stir well, boil, continue to stir for 48 hours, filter and concentrate the filtrate, add 50% of the prescription amount of benzalkonium chloride as a bacteriostatic agent, dissolve evenly to obtain solution A, and let it cool for later use; Dissolve Carbomer 941 in water for injection, heat up and dissolve under stirring to obtain solution B; add zinc gluconate to solution A to dissolve, then add borax and glycerin, stir to dissolve, add it to solution B, and boil and filter , to obtain solution C; take another water for injection, add borneol, β-carotene, vitamin E, Tween 80, stir evenly, dissolve to obtain solution D,...

Embodiment 2

[0044] Pearl layer powder 350g

[0045] Zinc gluconate 4.18g

[0046] β-carotene 0.003g

[0047] Vitamin E 1g

[0048] borneol 0.6g

[0049] Polyvinyl alcohol 20g

[0050] Tween 80 2g

[0051] Benzalkonium Bromide 1g

[0052] Sodium citrate 3g

[0053] Sodium chloride 6.8g

[0054] Add water for injection to 1000ml

[0055] Add pearl layer powder with water for injection, stir well, boil, continue to stir for 48 hours, filter, concentrate the filtrate to an appropriate amount, add 50% of the prescription amount of benzalkonium bromide as a bacteriostatic agent, dissolve evenly to obtain solution A, let it cool for later use Dissolve polyvinyl alcohol in water for injection, heat up and dissolve under stirring to obtain solution B; add zinc gluconate to solution A for dissolution, then add sodium citrate and sodium chloride, stir and dissolve, then add it to solution B , and boiled and filtered to obtain solution C; take another appropriate amount of water for injectio...

Embodiment 3

[0057] Pearl layer powder 350g

[0058] Zinc gluconate 4.18g

[0059] β-carotene 0.003g

[0060] Vitamin E 1g

[0061] borneol 0.6g

[0062] Carbomer 940 15g

[0063] Tween 80 2g

[0064] Benzalkonium Bromide 1g

[0065] Triethanolamine 18g

[0066] Glucose 38g

[0067] Add water for injection to 1000ml

[0068] Add pearl layer powder and water for injection, stir well, boil, continue to stir for 48 hours, filter, concentrate the filtrate to an appropriate amount, add 50% of the prescription amount of benzalkonium bromide, dissolve evenly to obtain solution A, let it cool for later use; take another injection Dissolve Carbomer 940 in water, add triethanolamine, heat up and dissolve under stirring to obtain solution B; add zinc gluconate to solution A to dissolve, add glucose, stir to dissolve, add it to solution B, and boil and filter to obtain solution C; Take another appropriate amount of water for injection, add borneol, β-carotene, vitamin E, and Tween 80, stir we...

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PUM

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Abstract

A medical gel for preventing and treating cataract contains the hydrolytic liquid of pearl powder, borneol, Zn, beta-carotene, VE, gel matrix and pharmacologically acceptable carrier. Its preparing process is also disclosed.

Description

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Claims

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Application Information

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Owner 湖北远大天天明制药有限公司
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