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Combination drug therapy to treat obesity

A composition and obesity technology, applied in the direction of active ingredients of heterocyclic compounds, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve problems such as not being able to help patients lose weight and maintain a stable weight

Inactive Publication Date: 2007-01-31
THERAKOS INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Pharmacological regimens that work initially often do not help many patients sustain weight loss or maintain a stable weight

Method used

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  • Combination drug therapy to treat obesity

Examples

Experimental program
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Effect test

Embodiment

[0081] The following examples illustrate therapeutic regimens and resulting synergistic effects by co-administering an anticholinesterase agent and an antidepressant to an individual to achieve long-term stable weight loss. Each patient is assigned an alphanumeric designator.

[0082] Patient A1

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Abstract

Provided are methods of achieving desirable weight loss in an overweight or obese individual by administering at least one anticholinesterase agent and at least one antidepressant. The invention also provides for pharmaceutical compositions and kits for simultaneous delivery of at least one anticholinesterase agent and at least one antidepressant.

Description

[0001] Cross References to Related Applications [0002] This application claims priority to US Provisional Patent Application 60 / 523,610, filed November 19, 2003, the contents of which are hereby incorporated by reference in their entirety. [0003] Statement Concerning Attribution of Rights to Inventions Made in Federally Sponsored Research and Development [0004] none Background of the invention [0005] Obesity is the most common nutritional disorder in the United States and perhaps in developed countries. Numerous studies have shown that excessive weight loss significantly reduces the risk of chronic diseases such as diabetes, hypertension, hyperlipidemia, coronary heart disease, and musculoskeletal disease. Current pharmacological treatments for obesity and weight loss include administration of selective serotonin reuptake inhibitors (SSRIs) together with the anorectic drug, benzfetamine (phentermine) (see, U.S. Patent 6,548,551); administration of optically pure Sib...

Claims

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Application Information

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IPC IPC(8): A61K31/135A61K31/445A61K31/27A61K31/55A61K31/343
Inventor 约翰·C·西德
Owner THERAKOS INC
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