Methods of modulating cytokine activity, related reagents
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- SCHERING AG
- Publication Date
- 2007-02-28
- Estimated Expiration
- Not applicable · inactive patent
Abstract
Description
[0001] This application claims the benefit of U.S. Provisional Patent Application no. 60 / 545,762, filed February 17, 2004, which is hereby incorporated by reference in its entirety. field of invention
[0001] The present invention generally relates to the use of mammalian cytokines. More specifically, the present invention discloses receptor subunits of the IL-27 receptor. Background of the invention
[0002] The immune system protects individuals against infectious agents such as bacteria, multicellular organisms, and cancer. This system includes several types of lymphoid and myeloid cells, such as monocytes, macrophages, dendritic cells (DCs), eosinophils, T cells, B cells, and neutrophils. These lymphoid and myeloid cells often produce signaling proteins called cytokines. The immune response includes inflammation, the accumulation of immune cells throughout the body or especially locally. In response to infectious or foreign substances, immune cells secrete cytokines,...