Application of Chinese medicine balloonflower as in-vitro spermaticide and method for preparing the medicament

A technology for killing spermatozoa and Platycodon grandiflorum, which is applied in the application field of traditional Chinese medicine Platycodon grandiflorum as an in vitro spermicidal drug, which can solve the problems of side effects, uncertainty of side effects, and inability to be widely used, and achieve the effect of convenient use and reliable contraceptive effect

Inactive Publication Date: 2007-05-23
SHANDONG PROVINCIAL FAMILY PLANNING INST OF SCI & TECH
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AI Technical Summary

Problems solved by technology

In response to this situation, there are many reports on the spermicidal drugs of traditional Chinese medicine compositions, but due to the uncertainty of its toxic and side effects, and many reasons such as low spermicidal efficacy, it cannot be widely used so far.
Some compounds have been reported to kill sperm, but because these contraceptives have multiple functions such as bactericidal, virucidal, and spermicidal, and are suitable for areas where sexually transmitted diseases and AIDS are common, there are still toxic and side effects for contraceptives that are purely spermicidal

Method used

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Embodiment Construction

[0012] The traditional Chinese medicine Platycodon grandiflorum of the present invention is used as a medicine for killing sperm in vitro, and the Chinese medicine Platycodon grandiflorum is used as a drug raw material for killing sperm outside the body, and its extract is made into emulsion or suppository for vaginal contraceptive medicine. The excipients and dosages used in the emulsion and suppository are conventional pharmaceutical excipients and dosages.

[0013] The preparation method of the Chinese medicine Bellflower as an in vitro spermicidal drug is: grind the Chinese medicine bellflower, place it in 0.9% normal saline and soak it for 1.5-2.5 hours, preferably 2 hours, and the ratio of bellflower raw material to normal saline is 100 grams : 900-1200 milliliters, preferably 100 grams: 1000 milliliters, placed in a metal bath at 100° C. and heated for 15-40 minutes, preferably 30 minutes, after taking out, filtering and removing slag to obtain Platycodon grandiflorum ex...

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Abstract

The invention relates to a method for preparing root of ballon flower into the drug that kills sperm externally. The root of ballon flower can kill sperm externally; therefore, the invention makes it into emulsion or bougie. And the production comprises that: breaking root of ballon flower, immerging in 0.9% normal saline at 100g: 900-1200ml, heating in metal bath at 100Deg. C, taking out, filtering, removing slag, to obtain extractive, and treating extractive into emulsion or bougie. The inventive extractive will not stimulate vaginal mucosa, and affect the vaginal bacterial, without side effect. And it can function long time.

Description

technical field [0001] The invention relates to a traditional Chinese medicine, which is an application of the traditional Chinese medicine platycodon grandiflorum as an in vitro spermicide and a method for preparing the medicine. Background technique [0002] Among the contraceptive measures, intrauterine device, tubal ligation and vasectomy will all cause harm to the human body. For this reason, people use condoms or oral contraceptives to minimize the damage. However, long-term oral contraceptives will cause harm to the human body. Produce bigger side effect, and the use of condom still has certain probability of conception except that sensory property is poor, so this area is trying hard to study the medicine of in vitro spermicide again in recent years. The drugs used to kill sperm in vitro were the first to use imported drugs, and later more varieties were launched in China. Since the main ingredients of the drugs are all western medicines, it was found during use that...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/34A61K9/02A61K9/107A61P15/18A61K125/00
Inventor 王磊光邱毅贾颐舫杨丹彤张爱东
Owner SHANDONG PROVINCIAL FAMILY PLANNING INST OF SCI & TECH
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