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Application of Chinese medicine lilac flower as in-vitro spermaticide and method for preparing the medicament thereof

A technology of male clove and spermicide, which is applied in the application field of traditional Chinese medicine male clove as an in vitro spermicide, can solve the problems of toxic and side effects, uncertainty of toxic and side effects, and inability to be widely used, etc., and achieves the effect of convenient use and reliable contraceptive effect

Inactive Publication Date: 2007-05-23
SHANDONG PROVINCIAL FAMILY PLANNING INST OF SCI & TECH
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AI Technical Summary

Problems solved by technology

In response to this situation, there are many reports on the spermicidal drugs of traditional Chinese medicine compositions, but due to the uncertainty of its toxic and side effects, and many reasons such as low spermicidal efficacy, it cannot be widely used so far.
Some compounds have been reported to kill sperm, but because these contraceptives have multiple functions such as bactericidal, virucidal, and spermicidal, and are suitable for areas where sexually transmitted diseases and AIDS are common, there are still toxic and side effects for contraceptives that are purely spermicidal

Method used

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Embodiment Construction

[0010] The Chinese medicine clove of the present invention is used as a medicine for killing sperm in vitro, wherein the medicine clove is used as a drug raw material for killing sperm in vitro, and its extract is made into emulsion or suppository for vaginal contraceptive medicine. The excipients and dosages used in the emulsion and suppository are conventional pharmaceutical excipients and dosages.

[0011] The preparation method of the Chinese medicine clove as an in vitro spermicidal drug is: grind the raw material of the Chinese medicine clove, place it in 0.9% normal saline and soak it for 1.5-2.5 hours, preferably 2 hours, the ratio of the raw material of clove to normal saline 100 grams: 900-1200 milliliters, preferably 100 grams: 1000 milliliters, placed in a metal bath at 100°C and heated for 15-40 minutes, preferably 30 minutes, taken out, filtered to remove slag to obtain male clove extract, and male clove extract It is prepared into emulsion or suppository with co...

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Abstract

The invention relates to a method for using cloves to kill sperm externally, wherein it uses cloves as the drug to kill sperm externally, makes extractive into emulsion or suppositorium, to be used in vagina contraceptive. And its production comprises that: breaking cloves, immerges in 0.9% normal saline, while their ration is 100g: 900-1200ml, to be heated in 100Deg. C metal bath; taking out, filtering out the slag. The inventive cloves extractive has non stimulation on vaginal mucosa, without damage on vaginal bacterial and side effect. And it has low cost.

Description

technical field [0001] The invention relates to a traditional Chinese medicine, and relates to the application of the traditional Chinese medicine clove as an in vitro spermicide and a method for preparing the medicine. Background technique [0002] Among the contraceptive measures, intrauterine device, tubal ligation and vasectomy will all cause harm to the human body. For this reason, people use condoms or oral contraceptives to minimize the damage. However, long-term oral contraceptives will cause harm to the human body. Produce bigger side effect, and the use of condom still has certain probability of conception except that sensory property is poor, so this area is trying hard to study the medicine of in vitro spermicide again in recent years. The drugs used to kill sperm in vitro were the first to use imported drugs, and later more varieties were launched in China. Since the main ingredients of the drugs are all western medicines, it was found during use that these drug...

Claims

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Application Information

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IPC IPC(8): A61K36/61A61K9/02A61K9/107A61P15/18
Inventor 贾颐舫邱毅王磊光张爱东何寿增
Owner SHANDONG PROVINCIAL FAMILY PLANNING INST OF SCI & TECH
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