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Fluid delivery device

A technology of fluid delivery and fluid, which is applied in the field of subocular fascia delivery devices, and can solve problems such as eye injury and blindness

Inactive Publication Date: 2007-06-06
ALCON INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Additionally, this activity may lead to inadvertent penetration of the sclera, allowing drug injection into the vitreous cavity.
What's more, penetrating the sclera can cause serious damage to the eye or even blindness

Method used

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Examples

Experimental program
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Effect test

Embodiment Construction

[0016] As best shown in FIGS. 1-3 , the drug delivery device 10 of the present invention generally includes a body 12 , a cylindrical body 14 , a nose cone or tip 16 , and a cannula 18 . The body 12 is generally hollow and its proximal end 20 is generally open and sized to receive a sealed vial 54 containing the drug to be delivered. The cylinder 14 is also generally hollow and has an interior cavity 22 . A nose cone or tip 16 fits over the cylinder 14 opposite the body 12 and holds a cannula 18 . Cannula 18 may be any suitable cannula, such as that described in US Patent No. 6,413,245 B1 (Yaacobi et al.). Piston 24 is generally sized to reciprocate snugly within cavity 22 , but includes a flange 26 having a plurality of paddles 28 sized to reciprocate within body 12 . The pick 28 fits in a slot 30 of the body 12 and allows the pick 28 to be gripped when the piston 24 is installed in the device 10 . The flange 26 engages the piston 24 with a spring 32 mounted in the body 12...

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PUM

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Abstract

A syringe-like device having a chamber in which a pressurizing piston reciprocates. The chamber is connected on one end to a vial containing a drug to be delivered to an eye and on the other end to a needle or cannula for administering the drug to an eye. Pulling proximally backwards on the piston creates a vacuum in the chamber and draws the drug out of the vial. Upon release of the piston, a spring pushes the piston forward, pressurizing the chamber and forcing the drug out of the cannula. A one-way valve prevents the drug from being expelled back into the vial. A pinch valve between the chamber and the cannula allows the flow of the drug out of the cannula to be stopped. The flow rate of the drug out of the cannula can be controlled by varying the size of the chamber, piston and spring.

Description

technical field [0001] The present invention relates generally to the delivery of pharmaceutically active agents useful in ophthalmic diseases to the back of the eye, and more particularly to a sub-Tenon delivery device for delivering a bolus to the back of the human eye near the macula. Background technique [0002] Some diseases and disorders of the back of the eye can endanger vision. Age-related macular degeneration (ARMD), choroidal neovascularization (CNV), retinopathy (eg, diabetic retinopathy, vitreoretinopathy), retinitis (eg, cytomegalovirus (CMV) retinitis), uveitis, Macular edema and glaucoma are some examples. [0003] Age-related macular degeneration (ARMD) is the leading cause of blindness in the elderly. ARMD attacks and blurs the center of vision, making reading, driving, and other fine tasks difficult or impossible. In the United States alone, 200,000 new cases of ARMD occur each year. Current estimates suggest that about 40 percent of people over the a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M5/00
CPCA61M2005/3115A61M5/329A61M2210/0612A61M2005/3128A61M5/3213A61F9/0017A61M5/1454
Inventor D·W·希金博特姆J·R·普雷斯科特M·A·齐卡
Owner ALCON INC
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