Sample adapter

a technology of analyte and adapter, which is applied in the field of determining the concentration of analyte within living tissue, can solve problems such as systematic errors in measurement results

Inactive Publication Date: 2005-03-31
RULE PETER +3
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Although the apparatus taught in the above-mentioned U.S. Pat. No. 6,198,949 has led to a significant advance in the state of the art of non-invasive blood glucose analysis, one possible source of error in such analysis arises due to physiological variation across the patient population.
This variation, as well as other factors, can introduce systematic error into the measurements being performed.

Method used

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Embodiment Construction

Although certain preferred embodiments and examples are disclosed below, it will be understood by those skilled in the art that the invention extends beyond the specifically disclosed embodiments to other alternative embodiments and / or uses of the invention and obvious modifications and equivalents thereof. Thus, it is intended that the scope of the invention herein disclosed should not be limited by the particular disclosed embodiments described below.

I. Overview of Analyte Detection Systems

Disclosed herein are analyte detection systems, including a noninvasive system discussed largely in part A below and a whole-blood system discussed largely in part B below. Also disclosed are various methods, including methods for detecting the concentration of an analyte in a material sample. The noninvasive system / method and the whole-blood system / method are related in that they both can employ optical measurement. As used herein with reference to measurement apparatus and methods, “optica...

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Abstract

An adapter presents a sample of bodily fluid, such as whole blood, including an analyte to an analyzer window of a non-invasive monitor. The adapter comprises a base material that comprises a first side and a second side. The adapter also comprises a sample accommodating volume extending between an opening in the second side of the base material and an opening in the first side of the base material.

Description

BACKGROUND OF THE INVENTION 1. Field of the Invention This invention relates generally to determining analyte concentrations within living tissue. 2. Description of the Related Art Millions of diabetics are forced to draw blood on a daily basis to determine their blood glucose levels. A search for a non-invasive methodology to accurately determine blood glucose levels has been substantially expanded in order to alleviate the discomfort of these individuals. SUMMARY OF THE INVENTION A significant advance in the state of the art of non-invasive blood glucose analysis has been realized by an apparatus taught in U.S. Pat. No. 6,198,949, titled SOLID-STATE NON-INVASIVE INFRARED ABSORPTION SPECTROMETER FOR THE GENERATION AND CAPTURE OF THERMAL GRADIENT SPECTRA FROM LIVING TISSUE, issued Mar. 6, 2001; and by methodology taught in U.S. Pat. No. 6,161,028, titled METHOD FOR DETERMINING ANALYTE CONCENTRATION USING PERIODIC TEMPERATURE MODULATION AND PHASE DETECTION, issued Dec. 12, 2000;...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61B5/00
CPCA61B5/14532A61B5/1495A61B5/1491A61B5/1455
Inventor RULE, PETERBRAIG, JAMES R.HARTSTEIN, PHILIP C.GABLE, JENNIFER H.
Owner RULE PETER
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