Non endocrine disrupting cytoprotective UV radiation resistant composition

Abstract

Compositions for enhanced UV-protective agents that increase immuno-responsiveness by providing cytoprotective additives for mammalian skin while also providing avoidance from endocrine disrupting agents are described. A composition comprising: (a) at least one inorganic sun-blocking agent, (b) optionally at least one non-endocrine disrupting sunscreen agent, (c) at least one non-endocrine disrupting emollient with or mixtures thereof and (d) an optional oil component comprising a carrier oil, preferably an essential oil of a naturally occurring substance and a method of making this and other versions of similar compositions is detailed. The compositions ares shown to be capable of protecting skin and mammalian health from the harmful effects of radiation including ultraviolet light or sunlight by inhibiting the loss of skin immunocompetency and eliminating any endocrine disrupting agents normally utilized as sunscreen agents.

Description

CLAIM TO PRIORITY [0001] Applicants hereby claim priority under all rights to which they are entitled under 35 U.S.C. Section 120 based upon the U.S. patent application Ser. No. 09 / 682,249, filed Aug. 9, 2001 Titled: NON-ENDOCRINE DISRUPTING CYTOPROTECTIVE UV RADIATION RESISTANT COMPOSITION, filed at the United States Patent and Trademark Office on Aug. 9, 2001 and subsequently filed as PCT application PCT / US02 / 24866 at the United States Patent and Trademark Office on Aug. 8, 2002.FIELD OF INVENTION [0002] This invention relates to new and useful ultraviolet radiation protective agents that can be used as beneficial sunscreens and sun-blocks in various compositions or formulations. The compositions include enhanced protection and increased immuno-responsiveness by providing cytoprotective additives for mammalian skin while also providing avoidance from endocrine disrupting agents. It has been determined as of 2001, that sunscreen agents used in almost all currently marketed and sold...

AI Technical Summary

Benefits of technology

[0005] Growing public awareness that the enjoyment of outdoor activities includes the need for adequate sun protection has led to an unprecedented growth in the area of sunscreen products. A very recent study by Margaret Schlumph from the Institute of Pharmacology and Toxicology at the University of Zurich, supports earlier health concerns regarding the use of endocrine disrupting organic substances in nearly all UV screening chemicals used in sunscreens. Additionally, the use of Aloe, or more specifically aloe barbadensis Miller has heretofore been known as a useful agent for the formulation of sunscreens as well as a substance that can both reduce UV damage to human skin that is inflamed and also promote healing. What was not well documented until recent publications and a subsequent U.S. Pat. No. 5,824,659 by Strickland and coworkers is that an extract found in all Aloe plants that is normally removed during carbon adsorptive processing, is capable of providing cyctoprotection to the mammalian skin. This extract boosts the immune system response of the skin, thereby significantly reducing the risk to various forms of skin cancer. There is strong evidence to suggest that this beneficial effect translates to skin in most mammals, thereby the present invention provides a possible preventative formulation for animals in zoos or other habitats where UV exposure could be hazardous to the animals' health.

[0056] Essentially, the compositions of this invention are easily made by simple mixing and provide an excellent dispersion of the inorganic based sunscreen / sunblock agent throughout the composition, thus ensuring even skin coverage. With the use of ultramarine pigments, after initial coloring effects, the compositions are substantially invisible upon application to the skin.

Problems solved by technology

Although a tan has long been considered a symbol indicative of good health and the ability to secure sufficient leisure time to enjoy many and numerous outdoor activities, it has become very evident that excessive exposure of the human skin to sunlight is harmful.