Supplementation or replacement of a nucleus pulposus of an intervertebral disc

a technology of intervertebral discs and nucleus pulposus, which is applied in the field of replacement or supplementation of the natural nucleus pulposus of the intervertebral disc, can solve the problems of pain and disability, high cost, and many lost work and expense, and achieve the effect of improving the function of the degenerated nucleus pulposus

Inactive Publication Date: 2006-06-08
DEPUY SYNTHES PROD INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0020] In another aspect, the invention provides a surgical approach to the nucleus for implantation of an implant that will prevent damage to the annulus.
[0025] In another aspect, the invention provides an implant that can improve the function of a degenerated nucleus pulposus of an intervertebral disc.

Problems solved by technology

Chronic back pain, typically lower back pain, is experienced by many individuals, and is responsible for much lost time at work and expense for treatment.
Degeneration of the nucleus leads to degradation and loss of function of the intervertebral disc, resulting in pain and disability.

Method used

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  • Supplementation or replacement of a nucleus pulposus of an intervertebral disc
  • Supplementation or replacement of a nucleus pulposus of an intervertebral disc
  • Supplementation or replacement of a nucleus pulposus of an intervertebral disc

Examples

Experimental program
Comparison scheme
Effect test

example

[0059] This example illustrates filling of a nucleus pulposus cavity in a spinal motion segment by the process of the invention. Various studies by the inventors have described the Poisson effect in a hydrogel and its usefulness in approximating the normal synergistic mechanical properties of the nucleus in interaction with the annulus. In order to achieve appropriate mechanical properties, proper filling of the disc core volume is essential.

[0060] A flexibility experiment was conducted by performing the process of the invention for replacing the nucleus pulposus. The flexibility of the spinal motion segment or unit was measured at various steps in the procedure in order to illustrate the simulated degeneration and restoration of the nucleus. An appropriate specimen of an L4 / L5 spinal motion segment was selected, including the L4 and L5 lumbar vertebrae and the intervertebral disc therebetween with intact annulus fibrosus and nucleus pulposus. The selected specimen had an essential...

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PUM

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Abstract

A degenerated nucleus pulposus located in a central core region of an intervertebral disc within the annulus fibrosus is supplemented or replaced by a method wherein an amount of a biocompatible material is introduced into the central core region by a process including the steps of 1) forming a channel through a vertebral body adjacent to said intervertebral disc, extending from an exterior surface of the vertebral body to the central core region of the annulus fibrosus; 2) introducing an amount of a biocompatible material through the channel into the central core region of the annulus fibrosus; 3) pressurizing the biocompatible material through the channel to a postsurgical pressure sufficient to alleviate symptoms caused by the degenerated nucleus pulposus; and 4) sealing the channel while maintaining the sufficient postsurgical pressure. After sealing the channel, a vertebroplasty may optionally be performed in the vertebra.

Description

CROSS-REFERENCE TO RELATED APPLICATION [0001] This application claims the benefit of U.S. Provisional Patent Application No. 60 / 591,094, filed Jul. 27, 2004, the entire disclosure of which is incorporated herein by reference.BACKGROUND OF THE INVENTION [0002] 1. Field of the Invention [0003] The present invention relates to methods and apparatus for replacing or supplementing the natural nucleus pulposus of an intervertebral disc by using a viscoelastic low-modulus implant through a transosseus approach, and more particularly to methods and apparatus for pressurizing a viscoelastic implant within the intervertebral disc to achieve an appropriate physiologic state of annulus tension and nucleus pressurization. [0004] 2. Brief Description of the Prior Art [0005] Chronic back pain, typically lower back pain, is experienced by many individuals, and is responsible for much lost time at work and expense for treatment. Such pain is generally the result of a pathological condition of an int...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61F2/44
CPCA61B17/86A61F2/28A61F2/442A61F2/4611A61F2002/2839A61F2002/30224A61F2002/30242A61F2002/444A61F2002/4445A61F2002/4627A61F2002/4631A61F2230/0069A61F2230/0071A61F2/46A61F2/44
Inventor VRESILOVIC, EDWARDKEANE, MICHAEL F.SCHAER, THOMAS P.
Owner DEPUY SYNTHES PROD INC
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