Methods of Treating Skin

a skin and skin technology, applied in the field of dermatological compositions, can solve the problems of skin elasticity decline and sagging, and achieve the effect of treating and protecting the skin

Inactive Publication Date: 2010-10-28
TRACIE MARTYN INT
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0012]In accordance therewith, a method and composition is provided for treating skin, comprising administering a topical composition to the skin, containing a lipoic acid, a carnitine, and a carnosine, or the dermatologically acceptable salt of any of these components in an amount effective to treat skin. Treating skin comprises treating skin damage and the signs of aging of the skin. The skin damage may be due to chronoaging or photoaging, and includes, for example, wrinkles, sagging skin, and decreased elasticity. Treating skin may also provide treatment of hyperpigmentation. One topical composition comprises R-lipoic acid and / or R-dihydrolipoic acid, acetyl-l-carnitine, carnosine, and a dermatologically acceptable carrier. Another embodiment of the invention provides a method for reducing mitochondrial decay in skin cells, comprising administering a topical composition to the skin, containing a lipoic acid, a carnitine, and a carnosine, or the dermatologically acceptable salt of any of these components in an amount effective to treat skin.
[0014]In a preferred embodiment, a liposome or similar carrier is used. This is useful in protecting the lipoic acid and other agents from oxidation before use.

Problems solved by technology

The skin damage may be due to chronoaging or photoaging, and includes, for example, wrinkles, sagging skin, and decreased elasticity.

Method used

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  • Methods of Treating Skin
  • Methods of Treating Skin

Examples

Experimental program
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Effect test

example 1

[0173]

Active Ingredient% by weightR-lipoic acid5.0acetyl-l-carnitine2.0carnosine1.0astaxanthin1.0tocotrienol0.50tocopherol0.50sesame oil1.0grape proanthocyanidin0.50E.D.T.A. (ethylenediamine tetracetic0.05acid)

example 2

[0174]

Ingredient% by weightR-lipoic acid1.0acetyl-l-carnitine1.0carnosine1.0benfotiamine0.2bilberry anthocyanins1.0rosmarinic acid0.5shark derived glycosaminoglycans1.0tocopherols0.5

example 3

[0175]

Ingredient% by weightR-dihydrolipoic acid1.0acetyl-l-carnitine2.0carnosine1.0lutein0.5tetrahexyldecylascorbate3.0lycopene0.5coenzyme Q10 (ubiquinone)0.1curcumine0.5

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PUM

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Abstract

A topical composition comprising a lipoic acid, a carnitine, and a carnosine in a suitable vehicle for topical application and a method for treating skin is provided. The present compositions are useful in improving the appearance of aged skin characterized by wrinkles and loss of elasticity. Preferred components include R-lipoic acid or R-dihydrolipoic acid, acetyl-l-carnitine, and l-carnosine.

Description

[0001]The present invention claims priority to U.S. Provisional Application No. 60 / 665,206 filed Mar. 24, 2005, herein incorporated by reference in it entirety.FIELD OF INVENTION[0002]The present invention relates to topical dermatological compositions and the topical application of such compositions for the prevention and / or treatment of damage to skin. This invention describes the application of topical compositions containing a lipoic acid, carnosine, and carnitine.BACKGROUND OF THE INVENTION[0003]Skin is subject to abuse by many extrinsic (environmental) factors as well as intrinsic factors. A common extrinsic factor is exposure to ultraviolet radiation. Whether extrinsic or intrinsic, the abuse results in skin aging. Skin aging happens in two ways: (1) through the natural aging process, which dermatologists call chronological aging (also known as chronoaging) and (2) through UV rays in sunlight accelerating the aging process, which doctors call photoaging. Chronoaging results i...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61K9/127A61K8/18A61K38/43A61K38/44A61Q19/00A61Q17/04A61Q19/08A61K31/385
CPCA61K8/41A61K8/44A61K8/4986A61K8/64A61K31/385A61Q17/04A61K2800/522A61Q19/08A61K8/11A61K8/14A61K8/4946A61K31/7008A61N5/0616A61N2005/0659A61N2005/0663A61K8/46A61K8/606A61K2800/10A61N1/327A61N1/328A61Q1/02A61Q1/10
Inventor MORARIU, MARIUS
Owner TRACIE MARTYN INT
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