4 results about "Acetyl-L-carnitine" patented technology

The application discloses a kind of high adhesion hydrogel for electroencephalogram test and its preparation method and application, belong to biomedical engineering technical field.The hydrogel includes the following components crosslinked product: anionic monomer, cationic monomer, monomer and mutual penetration agent;The anionic monomer is any one of malic acid, gluconic acid, citric acid and lactic acid, cationic monomer is betaine or acetyl L-carnitine, monomer is N, N-dimethyl acrylamide, acrylic acid, sodium acrylate, 4-acryloyl morpholine or sodium acrylamidomethyl propane sulfonate, mutual penetration agent is sodium chloride aqueous solution or sodium chloride water-retaining agent solution.Preparation, cationic monomer is mixed and dissolved, vacuum drying, adding photo initiator mixing, then mutual penetration agent is added, and it is obtained by ultraviolet light crosslinking.The hydrogel of the application has high adhesion (adhesion strength reaches 203.22 kPa), high ion mobility and excellent biocompatibility, and the signal gain in EEG and ECG test reaches 2-3 times of traditional conductive paste, which can be widely used in medical conductive paste field.

A moisture-proof acetyl-L-carnitine, comprising not less than 10% of acetyl-L-carnitine, or a hydrochloride thereof, or a mixture of both by weight. The preparation method comprises mixing the following components by prescription amount: acetyl-L-carnitine, or a hydrochloride thereof, or a mixture of both, one or more adjuvants selected from microcrystalline cellulose, compressible starch, lactose or mannitol, one or more adjuvants selected from silicon dioxide, magnesium stearate, calcium hydrogen phosphate, calcium silicate, and micro-powder silica gel; granulating; obtaining the moisture-proof acetyl-L-carnitine. The moisture-proof acetyl-L-carnitine is formulated into a nutritional supplement, a food, a beverage, or an animal feed.

The invention discloses a crystal form A of acetyl L-carnitine hydrochloride, a preparation method of the crystal form A, and a bulk drug, a food additive, a feed additive and a composition containing the crystal form A. The crystal form A of the acetyl L-carnitine hydrochloride is good in solubility, high in stability, high in purity, regular in shape and suitable for being applied to bulk drugs, food additives and feed additives. The preparation method is simple in process, the crystal form A can be obtained at high yield through in-situ crystallization of a reaction solution and dispersion of ethanol, and the preparation method is suitable for large-scale industrial production.

The invention provides a composition for improving type 2 diabetes mellitus complicated with depression as well as a preparation method and application of the composition, and relates to the technical field of medicines. The composition comprises the following components: a coptis chinensis extract, a hawthorn leaf extract, L-carnitine, acetyl L-carnitine and inulin. The coptis chinensis is subjected to first-time enzymolysis by using a compound enzyme 1, and then is subjected to second-time enzymolysis by using a compound enzyme 2; and after enzymolysis, performing ultrasonic-assisted extraction by using an ethanol solution to obtain the coptis chinensis extract. Carrying out first enzymolysis on the hawthorn by using a compound enzyme 3, and then carrying out second enzymolysis by using a compound enzyme 4; and after enzymolysis, carrying out microwave-assisted extraction by using an ethanol solution to obtain the hawthorn leaf extract. The composition has a synergistic effect of all the components in the aspects of improving the glucose metabolism function and depression behavioristics, can effectively reduce fasting blood glucose, insulin resistance indexes and glycosylated hemoglobin, increase the sweet water preference rate and shorten the immobility time of forced swimming and tail suspension experiments, and has a better effect of treating diabetes mellitus complicated with depression.