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4 results about "Iodine deficiency" patented technology

Iodine deficiency is a lack of the trace element iodine, an essential nutrient in the diet. It may result in metabolic problems such as goiter, sometimes as an endemic goiter as well as cretinism due to untreated congenital hypothyroidism, which results in developmental delays and other health problems. Iodine deficiency is an important global health issue, especially for fertile and pregnant women. And it is a preventable cause of intellectual disability.

Method for producing iodized micellar casein

PCT designated stageWO2025183592A1Peptide/protein ingredientsAntinoxious agentsPotassium persulfateIodine deficiency
Iodized micellar casein is produced by adding, to an aqueous solution of micellar casein, crystalline potassium iodide at a ratio of 1:7-1:9; holding the mixture for 5-10 minutes; adding to the mixture crystalline potassium persulphate at a ratio of 1:8-1:12 crystalline potassium persulphate to micellar casein mass; holding the mixture for 4-8 hours at a temperature of 18-25°С and a pH of 6.5-8.9 while constantly monitoring the molecular iodine content of the solution and periodically adding portions of crystalline potassium persulphate at a ratio of 1:12-1:24 crystalline potassium persulphate to micellar casein mass to continue the iodination reaction; removing residual inorganic salts from the resulting aqueous solution by microfiltration and diafiltration, followed by sterilizing microfiltration and freeze drying or spray drying. The method makes it possible to produce iodized micellar casein that is suitable for creating products for preventing iodine deficiency and optimizing iodine metabolism and for preventing and protecting against radiation poisoning.
Owner:SOLOVEV VLADIMIR BORISOVICH +5

Composition for preventing iodine deficiency and optimizing iodine metabolism

PCT designated stageWO2025206981A1Powder deliveryPeptide/protein ingredientsIodine deficiencyFood industry
The invention relates to the medical and food industries, and more particularly to a composition for preventing iodine deficiency and optimizing iodine metabolism. The claimed composition for preventing iodine deficiency and optimizing iodine metabolism comprises, as an active agent, iodized micellar casein in an amount equivalent to 1-50 µg of iodine per kilogram of body weight per serving, in combination with a pharmaceutically acceptable carrier. The invention makes it possible to produce an effective composition that is highly soluble and exhibits long-term storage stability.
Owner:SOLOVEV VLADIMIR BORISOVICH +1

Thyroid function regulating preparation based on astragalus mongholicus fermentation extract and preparation method of thyroid function regulating preparation

The invention relates to the technical field of traditional Chinese medicine preparations, and particularly discloses a thyroid function regulation and control preparation based on an astragalus membranaceus fermentation extract and a preparation method thereof, and the preparation is technically characterized in that the preparation takes an extract obtained after astragalus membranaceus is fermented by specific microorganisms (such as lactobacillus plantarum) as an active ingredient. Systematic iodine deficiency rat model experiments prove that the fermentation extract has obviously better effects in the aspects of improving thyroid functions and forms (such as adjusting FT3, FT4, TSH and TPO-Ab), enhancing body antioxidant ability (such as improving activity of SOD and CAT of hippocampus and liver) and improving learning and memory behaviors than a traditional astragalus extract. The invention provides an effective scheme for developing an innovative traditional Chinese medicine preparation for comprehensively preventing and treating the iodine deficiency thyroid disease and complications thereof.
Owner:CANGZHOU MEDICAL COLLEGE

A BiOI with iodine deficiency 1-x Rod-shaped materials, their preparation methods and applications

ActiveCN117384387BSynthetic raw materials are cheap and easy to obtainlow costIodine deficiencyTricarboxylic acid
The application provides a BiOI with iodine defects 1‑x Rod-like material, preparation method and application thereof. Bismuth nitrate pentahydrate and 1,3,5-benzene tricarboxylic acid are added into methanol in proportion, and a metal organic framework [Bi9(C9H3O6)·9(H2O)9] is synthesized by heating at 100-140 DEG C for 20-24 h; the metal organic framework is mixed with ammonium iodide in proportion, and then is subjected to water bath at 60-100 DEG C for 0.5-1.5 h to derive rod-like BiOI; the obtained BiOI is calcined in a muffle furnace at 350-450 DEG C to obtain the rod-like BiOI material with iodine defects, which is represented as BiOI 1‑x . The material has the rod-like microstructure of the precursor [Bi9(C9H3O6)·9(H2O)9], the axial size is slightly reduced, the diameter of the rod is about 1-2 microns, the length is about 3-8 microns, the surface is rough, and the material has a porous structure. The material can be used as a photocatalyst for degradation of gaseous formaldehyde and liquid tetracycline, and both have excellent degradation performance.
Owner:BEIJING UNIV OF CHEM TECH