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Yitongshu drop pill for treating pain and its preparation method

A technology of dripping pills and traditional Chinese medicine, which is applied to medical preparations containing active ingredients, pill delivery, pharmaceutical formulations, etc. Stimulates symptoms, improves bioavailability, and accelerates dissolution and absorption

Inactive Publication Date: 2007-11-14
北京博智绿洲医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Oral liquid has the characteristics of low drug content, large dosage, inaccurate dosage, inconvenient taking and high production cost, and it is not easy to carry out
Although traditional Chinese medicine mixture is a traditional dosage form of traditional Chinese medicine, due to its backward preparation process, the utilization rate and bioavailability of raw materials and auxiliary materials are low, it cannot meet the requirements of large-scale industrial production; in addition, its dosage is large, and it is difficult to store, carry and use. convenient
[0014] In addition, conventional oral dosage forms, such as tablets, capsules, etc., will produce relatively large dust pollution due to the granulation process in the preparation process, which will cause harm to the health of the staff to a certain extent, and will also cause harm to the human body. some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0040] Now with several groups of specific examples, the preparation method of Yitongshu dripping pills of the present invention will be further described.

[0041] Group 1: Tests with a single matrix

[0042] 1. Weigh a certain amount of traditional Chinese medicine raw materials according to the ratio given in [Preparation Method] 1, and then follow the section [Appendix: Preparation Method of a Chinese Medicine Extract] to first prepare the traditional Chinese medicine Asarum, Angelica, Chuanxiong, Notopterygium, and Duhuo Extract dry powder of active ingredients such as , Fangfeng, Angelica dahurica and so on for future use;

[0043] 2. Substrate: polyethylene glycol (2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, β-cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc. pharmaceutical carrier;

[0044] 3. Proportion—in g or kg, in parts by weight, drug extract: matrix = 1:1~1:...

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PUM

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Abstract

The disclosed drop pill is a medicinal composition with the functions of dispersing pathogenic wind, promoting blood circulation, easing pain, and can be applied for treating pains caused by various reasons, the composition has the advantages of high biological availability, quick-speed medicine release, quick-speed effect, less toxic and side effects, higher medicinal content, smaller amount of administration, accurate administration dosage, easy administration, low price, and facilitated carrying. The medicine is prepared through the conventional drop pill preparing process.

Description

technical field [0001] The present invention relates to an analgesic effect of expelling wind, dispersing cold and eliminating dampness, activating blood circulation, dispelling blood stasis and analgesia, which is used for treating headache, toothache, neuralgia, rheumatic pain and fibromyalgia caused by various causes, bone joints, gastrointestinal tract, gallbladder and kidney. A pharmaceutical composition that causes pain due to diseases, cancers, etc., especially relates to an oral preparation that is formulated based on the prescription of Yitongshu injection, a traditional Chinese medicine prescription. Background technique [0002] According to the pharmaceutical standard WS 3 -Yitongshu injection prepared according to the formula and extraction process given in B-3180-98 is a medicine used to treat headache, toothache, neuralgia, rheumatic pain, myofibritis, bone and joint pain caused by various reasons , gastrointestinal, gallbladder, kidney disease, cancer and ot...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/20A61K36/264A61K36/238A61K36/237A61K36/236A61K36/232A61P29/00A61P25/04A61P1/02
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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