Laggera pterodonta buccal tablet, its preparation process and quality control method

A determination method and a technique for Lingdancao are applied in the field of traditional Chinese medicine preparations and their preparation methods and in the field of quality control of the preparations, which can solve problems such as insufficient quality control, and achieve the effects of preventing influenza, definite curative effect and broad application prospects.

Inactive Publication Date: 2009-08-12
SOUTH CENTRAL UNIVERSITY FOR NATIONALITIES +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above methods are not enough to control its quality

Method used

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  • Laggera pterodonta buccal tablet, its preparation process and quality control method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] A lingdancao buccal tablet, the main component is the traditional Chinese medicine lingdancao, and the added auxiliary materials are a combination of various substances such as non-dairy creamer, aspartame, menthol, magnesium stearate, etc.; after pressing the tablet, it is wrapped with a film Coating, the coating material is film coating premix.

[0028] The combination of dry panacea powder and auxiliary materials and the ratio of parts by weight are: 30 parts of dry panacea powder, 28 parts of non-dairy creamer, 3 parts of aspartame, 2.5 parts of menthol, magnesium stearate 1.5 parts, 0.5 parts of volatile oil.

[0029] The preparation method of buccal tablet is:

[0030] Take 5000g of panacea, steam distill, collect its volatile oil, filter the distilled aqueous solution, and use the filtrate for later use; decoct the dregs with water twice, each time for 1.5-2 hours, filter, combine the filtrate three times, and evaporate below 80°C Concentrate to a thick paste, ...

Embodiment 2

[0032] A lingdan grass buccal tablet, the main component is the traditional Chinese medicine lingdan grass, and the added auxiliary materials are: a combination of various substances such as non-dairy creamer, aspartame, menthol, magnesium stearate, etc., compressed into tablets and then packaged Film coating, the coating material is film coating premix.

[0033] The combination of dry panacea powder and auxiliary materials and the ratio of parts by weight are: 30 parts of dry panacea powder, 28 parts of non-dairy creamer, 3 parts of aspartame, 2.5 parts of menthol, magnesium stearate 1.5 parts, 1.0 parts of volatile oil.

[0034] The preparation method of buccal tablet is:

[0035] Take 5000g of panacea, steam distill it, collect its volatile oil, filter the distilled aqueous solution, and use the filtrate for later use; the volatile oil is clathrated with β-cyclodextrin, the specific method is: take an appropriate amount of β-cyclodextrin 120g, add distilled water to prepar...

Embodiment 3

[0037] A lingdancao buccal tablet, the main component is the traditional Chinese medicine lingdancao, and the added auxiliary materials are sucrose, lactose, xylitol, stevioside, menthol, and magnesium stearate. Film coating, the coating material is film coating premix.

[0038] The combination of dry panacea powder and auxiliary materials and the ratio of parts by weight are: 30 parts of dry panacea powder, 10 parts of xylitol, 10 parts of sucrose, 10 parts of lactose, 5 parts of cyclamate, 2.5 parts of menthol parts, 1.5 parts of magnesium stearate, and 2.0 parts of volatile oil.

[0039] The preparation method of buccal tablet is:

[0040]Take 5000g of panacea, steam distill, collect its volatile oil, filter the distilled aqueous solution, and use the filtrate for later use; decoct the dregs with water twice, each time for 1.5-2 hours, filter, combine the filtrate three times, and evaporate below 80°C Concentrate to a thick paste, about 30% water content or semi-solid aft...

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Abstract

The invention relates to a lingdancao buccal tablet, a preparation method thereof and a method for determining the content of wormwood in a lingdancao preparation. The lingdancao buccal tablet is a buccal tablet made of a traditional Chinese medicine lingdancao and appropriate amount of auxiliary materials. The buccal tablet is absorbed through the oral mucosa, and is used for treating pharyngitis, tonsillitis and other upper respiratory tract inflammations with quick effect, good curative effect and high bioavailability. In addition, the present invention also discloses a method for determining the content of fenoxin in Lingdancao buccal preparations, the method is as follows: the flavonoid compound fennel is obtained through repeated extraction and separation from Lingdancao buccal tablets, and it is used as a reference substance, High performance liquid chromatography was used to determine the content of Aisu in Lingdancao preparation. The method is simple, rapid, high in accuracy and good in reproducibility, and has strong practicability in the production and quality control of panacea preparations.

Description

[0001] The invention relates to a traditional Chinese medicine preparation, a preparation method thereof and a quality control method of the preparation, in particular to a lingdancao buccal tablet, a preparation method thereof and a quality control method of the lingdancao buccal tablet. Background technique [0002] Lingdan Grass, also known as Stinking Dan, is the dry aboveground part of Laggera pterodonta (DG.) Benth. Harvest in autumn when the stems and leaves are lush, and dry in the shade. Recorded in the Chinese Pharmacopoeia in 1977, it is recorded in historical records that panacea has been used as folk medicine for more than 500 years. "Southern Yunnan Materia Medica" records that it has the effects of "curing wind-heat accumulation toxin, carbuncle, boil, scabies, leukoplakia sore"; modern pharmacological research believes that it has anti-viral, anti-bacterial, anti-inflammatory, cough-relieving and expectorant effects. Panacea has been made into various oral pre...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/287A61K9/28A61P17/02A61P17/00G01N30/02A61K127/00
Inventor 梅之南高家雄冯云典杨光忠李效宽李芸芳
Owner SOUTH CENTRAL UNIVERSITY FOR NATIONALITIES
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