Antineoplastic composition, and process for preparing the same

A composition and anti-tumor technology, applied in the field of anti-tumor pharmaceutical composition and its preparation process, to achieve profound social benefits

Inactive Publication Date: 2007-07-25
云南天秀植物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

This patented technology allows for high yielding preparations from natural sources like rhodiola roots or Ginseng radixes while also producing other valuable materials such as gensenoids (the root) which are used widely throughout medicine today due to their beneficial properties. By changing only one part called either an active ingredient or a functionally important chemical compounds can be made more effective than traditional methods.

Problems solved by technology

This patents discusses how it may become important to study safety and efficacy of novel chemical compounds called gensenoids because they could potentially lead to potential treatments against certain types of diseases such as breast cancer. However, current methods involve extracting pure substances with high cost and poor yield rates due to limitations associated with conventional extraction techniques like solvent evaporation technique.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0077] Embodiment 1: the preparation of injection

[0078] Ginsenoside Rh 2 20kg, Ginsenoside Rg 3 40kg, with 240kl distilled water for injection, add about 3%-5% of Tween-80, stir well; then add 60kg of ginsenoside Rh crushed into fine powder 2 and ginsenoside Rg 3 Composition, heated to dissolve, filtered, subpackaged in ampoules, sterilized; made per milliliter containing ginsenoside Rh 2 0.5mg, Ginsenoside Rg 3 1 mg injection.

[0079] The above-mentioned ginsenoside Rh 2 and ginsenoside Rg 3 It can be purchased from the market or prepared as follows:

[0080] Take ginseng or notoginseng coarse powder of 10 mesh, reflux extraction with 70% ethanol for 3 times, each time for 2 hours, collect the extract, filter, and recover ethanol from the filtrate until there is no ethanol smell, concentrate in vacuum for 2 hours, add the concentrated solution to an equal volume Distilled water, stirred evenly, filtered, and the filtrate was adsorbed through a macroporous adso...

Embodiment 2

[0081] Embodiment 2: the preparation of capsule

[0082] Ginsenoside Rh 2 20kg, Ginsenoside Rg 3 80kg, take ginsenoside Rh 2 and ginsenoside Rg 3 Composition fine powder 100kg, add microcrystalline cellulose fine powder 900kg, fully stir and mix evenly, pack in the empty capsule; Make every capsule containing ginsenoside Rh 2 10mg, Ginsenoside Rg 3 20mg capsules.

Embodiment 3

[0083] Embodiment 3: the preparation of tablet

[0084] Ginsenoside Rh 2 30kg, Ginsenoside Rg 3 70kg, take ginsenoside Rh 2 and ginsenoside Rg 3 Composition fine powder 100kg, add microcrystalline cellulose fine powder 900kg, and add 5% starch, fully stir and mix evenly, granulate with dilute starch paste, dry; Add appropriate amount of magnesium stearate, granulate with 40 mesh sieve, mix Press evenly, film-coat, and pack; each tablet contains ginsenoside Rh 2 10mg, Ginsenoside Rg 3 20 mg tablet.

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PUM

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Abstract

An antineoplastic composite medicine in the form of injection, capsule, tablet, etc for treating cancer contains ginsenoside Rh2 and ginsenoside Rg3. Its preparing process includes such steps as purifying the saponin in protopanoxadiol group, dissolving them in the solution of acid, selective hydrolyzing, collecting the resultant substance, purifying, and conventional processing.

Description

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Claims

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Application Information

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Owner 云南天秀植物科技有限公司
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