Concatenate antigen membrane detecting kit and its preparing method

A detection kit and antigen technology are applied in the field of rheumatoid arthritis multi-antigen patch method detection kits, which can solve the problems of insufficient detection sensitivity and specificity, cumbersome operation, etc. Simple operation, strong practical effect
CN101025418AInactive Publication Date: 2007-08-29SHANGHAI KEXIN BIOTECH
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Patent Information

Authority / Receiving Office
CN Β· China
Current Assignee / Owner
SHANGHAI KEXIN BIOTECH
Publication Date
2007-08-29
Estimated Expiration
Not applicable Β· inactive patent

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Abstract

The invention relates to a test reagent box of multiple antigen membrane method which is used for diagnosing RA, it includes tablets and response groove, the tablets hold on the response groove; the tablets gap corresponding to the response groove gap; there is multi-personal reaction zone on the tablets which correspond with the multi-groove of reaction groove, there is a gap on the top of each groove; membrane bar test paper adhere to each reaction zone and with RA correlate antigen and response control belt; the RA related antigen is the corresponding antigen of RF, anti-CCP, anti-RA-33 antibody, anti-Sa antibody, anti-P68 or more than four kinds of antigen in antigen epitope polypeptide or antigen epitope polypeptide, the response control belt is a mixture of man IgG and man IgM. The reagent box in this invention overcome the lack of detection sensitivity and Specificity of the single autoantibody and the red tape of several autoantibody detection in a single operation, it provide the accuracy and convenience of RA diagnosis. The invention also disclosed the method of how to make the test box.
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Description

technical field

[0001] The present invention relates to a rheumatoid arthritis (RA) multi-antigen patch method detection kit and a preparation process thereof, more specifically relates to making a plurality of antigens related to rheumatoid arthritis on the detection kit, It is used to detect whether there are autoantibodies related to rheumatoid arthritis in human serum. Background technique

[0002] Rheumatoid arthritis (hereinafter referred to as RA) is the most common systemic autoimmune disease mainly characterized by chronic polyarticular inflammation. The sickness rate of this disease in my country is about 0.36%, and the patient age of onset is mostly in 20-50 years old, and the female is more than the male, and the ratio of male to female is 1: 3. Its prominent early clinical manifestations are symmetrical polyarticular redness, swelling, heat pain, small joints of extremities, proximal interphalangeal joints swelling, metacarpophalangeal (plantar toe), wrist, elb...

Claims

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