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Hepatosis-treating Chinese traditional medicine

A technology for Chinese patent medicines and liver diseases, which is applied in sugar-coated pills, drug combinations, and pharmaceutical formulas. It can solve the problems of difficult control of the production process and achieve stable and reliable drug quality, improved fluidity, and easy-to-control content standards.

Active Publication Date: 2011-01-12
涂跃飞
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  • Abstract
  • Description
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AI Technical Summary

Problems solved by technology

However, it still has the following disadvantages: the dose is slightly too large, 6 to 8 tablets are taken each time, and the amount of auxiliary materials is more than 3 times that of the main drug. If new auxiliary materials can be used to reduce the dosage, it will be convenient for patients; There is no content control standard for Zhongwurenol extract, and the production process is not easy to control, so the quality standard must be improved

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0017] Specific embodiments of the present invention will be described in detail below.

[0018] Silymarin (Silybin, Silymarin, LEGALON) is a loose powder obtained from the fruit of Silybum mariaum Gaertn., a plant of the genus Silybum in the family Asteraceae, which is processed and extracted from oil. Its main active ingredient is silybin (a stereoisomer), which belongs to flavonoid lignans, is a white crystalline powder, odorless, slightly bitter taste, hygroscopic; soluble in acetone, ethyl acetate Esters, methanol, ethanol, hardly soluble in chloroform, insoluble in water; easily soluble in dilute alkali solution.

[0019] Silybin

[0020] Wurenchun extract: the extract obtained by alcohol extraction of Schisandra chinensis (the dry mature fruit of Schisandra chinensis (Turcz.) Baill, a plant of Magnoliaceae, commonly known as "Northern Schisandra"). Schisandra chinensis mainly contains compounds such as schisandrin A, schisandra B, schisandrin C, schisandra alcohol A...

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Abstract

The Chinese medicine for treating hepatosis is prepared with silymarin 40-80 weight portions, alcohol extractum of five kinds of seed 140-180 weight portions, beta-cyclodextrin 120-160 weight portions and fine silica gel powder 10-20 weight portions. The Chinese medicine with beta-cyclodextrin and fine silica gel powder as supplementary material and prepared through specific production process has raised bioavailability, reduced dosage, easy-to-control production process and stable and reliable quality. The present invention also relates to the preparation process of the Chinese medicine.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a Chinese patent medicine for treating liver diseases. Background technique [0002] At present, milk thistle and Wurenchun extract are commonly used as a kind of Chinese patent medicine for the treatment of liver diseases. The medicine is also called compound Yiganling. It is used for hypochondriac pain, anorexia, abdominal distension, backache and fatigue, yellow urine and other symptoms caused by liver and kidney yin deficiency, dampness and poison; or chronic hepatitis with elevated transaminase; compound Yiganling, as a liver disease drug, has a good clinical response and is used in It is superior to Yiganling and Wurenchun single prescription preparations in terms of repairing liver cells and lowering enzymes without rebounding. It is an excellent Chinese patent medicine variety in the liver disease treatment drugs currently on the market. However, it still has...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/57A61K9/20A61K9/28A61K9/48A61K47/40A61P1/16A61K31/357
Inventor 黄云龙海燕涂跃飞
Owner 涂跃飞
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