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Chinese medicine preparation for treating gynecopathy and its preparing process

A technology of traditional Chinese medicine preparations and gynecological diseases, which is applied in the field of traditional Chinese medicine preparations and preparations for treating gynecological diseases, and can solve problems such as difficulty in swallowing, low bioavailability, and poor stability for patients

Active Publication Date: 2007-09-19
INCREASEPHARM HENGQIN INST CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Currently marketed dosage forms include pills, tablets, and capsules. These dosage forms are difficult for some patients to swallow, and the dosage is relatively large, and there are disadvantages such as poor stability and low bioavailability; the present invention is based on the prior art. The secondary development of traditional Chinese medicine theory and modern science and technology has disclosed a new dosage form with high bioavailability and low irritation

Method used

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  • Chinese medicine preparation for treating gynecopathy and its preparing process
  • Chinese medicine preparation for treating gynecopathy and its preparing process

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0118] Guizhi 600g, Poria cocos 600g, Moutan bark 600g, peach kernel 600g, white peony root 600g

[0119] For the above five flavors, take 480g of Poria cocos, grind them into fine powder; add 12 times the amount of water to the cortex of Moutan, soak in warm for 2 hours, steam distillation for 5 hours, collect the distillate, separate the volatile components, refrigerate overnight, and use the dregs for later use; The ingredients were clad with beta-cyclodextrin (paeonol-beta-cyclodextrin-water=1:10:100, stirred at 50°C for 4 hours), refrigerated overnight, filtered, and dried at low temperature (40°C) , crushed into fine powder; medicinal dregs, cassia twig, white peony root, peach kernel and remaining poria cocos were extracted twice with 90% ethanol, each time adding 5 times the amount of alcohol for 1.5 hours, combined extracts, recovered ethanol until it had no alcohol smell, Concentrate under reduced pressure to an appropriate amount; decoct the dregs with water twice, ...

Embodiment 2

[0121] Guizhi 600g, Poria cocos 600g, Moutan bark 600g, peach kernel 600g, white peony root 600g

[0122] For the above five flavors, take 480g of Poria cocos, grind them into fine powder; add 12 times the amount of water to the cortex of Moutan, soak in warm for 2 hours, steam distillation for 5 hours, collect the distillate, separate the volatile components, refrigerate overnight, and use the dregs for later use; The ingredients were clad with beta-cyclodextrin (paeonol-beta-cyclodextrin-water=1:10:100, stirred at 50°C for 4 hours), refrigerated overnight, filtered, and dried at low temperature (40°C) , crushed into fine powder; medicinal dregs, cassia twig, white peony root, peach kernel and remaining poria cocos were extracted twice with 90% ethanol, each time adding 5 times the amount of alcohol for 1.5 hours, combined extracts, recovered ethanol until it had no alcohol smell, Concentrate under reduced pressure to an appropriate amount; decoct the dregs with water twice, ...

Embodiment 3

[0124] Guizhi 240g, Poria cocos 240g, Moutan bark 240g, peach kernel 240g, white peony root 240g

[0125] For the above five flavors, take 192g of Poria cocos, grind them into fine powder; add 12 times the amount of water to the cortex of Moutan, soak in warm for 2 hours, steam distillation for 5 hours, collect the distillate, separate the volatile components, refrigerate overnight, and use the dregs for later use; The ingredients were clad with beta-cyclodextrin (paeonol-beta-cyclodextrin-water=1:10:100, stirred at 50°C for 4 hours), refrigerated overnight, filtered, and dried at low temperature (40°C) , crushed into fine powder; medicinal dregs, cassia twig, white peony root, peach kernel and remaining poria cocos were extracted twice with 90% ethanol, each time adding 5 times the amount of alcohol for 1.5 hours, combined extracts, recovered ethanol until it had no alcohol smell, Concentrate under reduced pressure to an appropriate amount; decoct the dregs with water twice, ...

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Abstract

The invention relates to a traditional chinese medicine preparation for treating gynecologic diseases and a preparing process thereof. The preparation comprises efficacious components mainly including cassia twig, tuckahoe, white paeony root, semen persicae and cortex moutan, and / or a carrier acceptable in pharmacy, with effect of promoting blood circulation, removing blood stasis and Xiao Zheng for treating various gynecologic diseases. The preparation of the invention is mainly in micro-pill, concentrated pill and dispersible tablet form, wherein the micro-pill / concentrated pill has less dosage, high bioavailability, little irritability, fine liquidity, even size, convenience for coating and dividing dose, while the dispersible tablet has various manners for taking the medicine, convenience for being taken, high bioavailability and the like; the preparing process of the invention is feasible, which is directly adapted to instruct large scale production.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation for treating gynecological diseases and a preparation method thereof, belonging to the technical field of traditional Chinese medicine. technical background [0002] With the continuous development of social economy, the continuous improvement of living standards, and the continuous enhancement of health care awareness, women are paying more and more attention to their own health. In addition, the incidence of female gynecological inflammation is very high, and they are prone to repeated infections. According to the Ministry of Health Survey statistics show that the incidence rate of gynecological diseases is as high as 75%, and the market of gynecological drugs is very promising with considerable market potential. [0003] Guizhi Fuling Pills was recorded in "Synopsis of the Golden Chamber" by Zhang Zhongjing in the Han Dynasty. This prescription has been clinically used for thousands...

Claims

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Application Information

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IPC IPC(8): A61K36/736A61K9/20A61K9/16A61P15/00
Inventor 张保献
Owner INCREASEPHARM HENGQIN INST CO LTD
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