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Process of extracting flavone from side product of orange processing

A by-product, citrus technology, applied in sugar derivatives, pharmaceutical formulations, plant raw materials, etc., can solve the problems of long production time, little extraction and utilization, and no classification, to improve efficiency, improve extraction efficiency, reduce The effect of production costs

Inactive Publication Date: 2010-05-26
ZHEJIANG ACADEMY OF AGRICULTURE SCIENCES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, most of them are concentrated on hesperidin and naringin, and there are not many other citrus flavonoids extracted and utilized; the national patent "citrus flavonoid extraction technology (03135524.2)" does not classify the extraction of flavonoids, and the product It is mainly flavonoid glycosides, and the method adopts a complex solvent, and the production time is long, and it only takes 72 hours to crystallize once.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Embodiment 1, a kind of method for extracting flavonoids from citrus processing by-products, carries out following steps successively:

[0018] 1) Preparation of raw materials: drying the citrus by-product (citrus peel) at 55° C., pulverizing, passing through a 40-60 mesh sieve to obtain the pulverized product.

[0019] 2) Extraction: put 0.5kg of pulverized material and 3L of 80% ethanol solution into an extraction kettle, and extract for 15min at a pressure of 10Mpa and a temperature of 70°C. After the extraction is completed, filter to obtain a supernatant; concentrate the supernatant in vacuo to obtain a crude extract.

[0020] 3) Primary separation: Suspend and dissolve 6 g of the above crude extract in 400 mL of water to form a suspension for later use.

[0021] Take the treated polyamide resin (60-80 mesh) and wet pack it into a column (1 cm inner diameter) with 95% ethanol, and the column volume is 30 mL. First use ethanol to flow and wash the column until the...

Embodiment 2

[0026] Embodiment 2, a method for extracting flavonoids from citrus processing by-products, the following steps are carried out successively:

[0027] 1) Preparation of raw materials: drying the citrus by-product (huyou peel) at 60° C. and then pulverizing it, passing through a 40-60 mesh sieve to obtain the pulverized product.

[0028] 2) Extraction: put 0.5kg of pulverized material and 5L of 85% ethanol solution into an extraction kettle, and extract at a pressure of 15Mpa and a temperature of 60°C for 10min. After the extraction is completed, filter to obtain a supernatant; concentrate the supernatant in vacuo to obtain a crude extract.

[0029] 3) Primary separation: Suspend and dissolve 7.5 g of the above crude extract with 1000 mL of water to form a suspension for later use.

[0030] Take the treated polyamide resin (60-80 mesh) and wet pack it into a column (inner diameter 2.5 cm) with 95% ethanol, and the column volume is 100 mL. First use ethanol to flow and wash th...

Embodiment 3

[0034] Embodiment 3, a kind of method for extracting flavonoids from citrus processing by-products, carries out following steps successively:

[0035] 1) Raw material preparation: the by-products of citrus processing (a mixture of citrus peels, meridians and processed orange pomace, etc.) are dried at 50° C., then pulverized, and passed through a 40-60 mesh sieve to obtain a pulverized product.

[0036] 2) Extraction: put 0.5kg of pulverized material and 2.5L of 75% ethanol solution into an extraction kettle, and extract for 12min at a pressure of 6Mpa and a temperature of 80°C. After the extraction is completed, filter to obtain a supernatant; concentrate the supernatant in vacuo to obtain a crude extract.

[0037] 3) Primary separation: Suspend and dissolve 2 g of the above crude extract in 400 mL of water to form a suspension for later use.

[0038] Take the treated polyamide resin (60-80 mesh) and wet pack it into a column (1 cm inner diameter) with 95% ethanol, and the c...

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PUM

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Abstract

The present invention discloses process of extracting flavone from side product of orange processing. The process includes the following steps: 1. crushing the side product into powdered material; 2.extracting the powdered material with alcohol solution, filtering and vacuum concentrating to obtain coarse extract; 3. initial separating through gradient eluting of the suspension comprising the extract and water in a polyamide column and sectionally collecting the eluted liquid; 4. purifying; and 5. vacuum concentrating the sectionally collected eluted liquid to obtain flavones of different types. The process has high flavone extracting speed and high product purity.

Description

technical field [0001] The invention relates to a method for extracting flavonoids from citrus processing by-products. Background technique [0002] Citrus is one of the main fruits in my country's fruit tree industry, widely distributed in Zhejiang, Fujian, Guangdong and other places. Its cultivation area ranks first in the world, and its output ranks third in the world. Citrus is rich in flavonoid substances. There are more than 60 kinds of flavonoid monomers that have been identified so far, which can be divided into flavanones, flavones, flavonols, flavanone alcohols, etc. Citrus is rich in flavonoids. Citrus flavonoids have various health care and medical functions such as anti-oxidation, anti-tumor, and cardiovascular and cerebrovascular protection, and have broad application prospects. [0003] With the development of canning and fruit juice processing industries, a large number of by-products of citrus processing are produced, which provide abundant raw materials f...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C07H17/07C07D311/04A61K36/752
Inventor 张玉吴慧明
Owner ZHEJIANG ACADEMY OF AGRICULTURE SCIENCES