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Medicinal composition with tumor inhibition function and preparation method and application thereof

A composition and drug technology, applied in the field of pharmaceutical composition and its preparation, can solve the problems of damaged tissue cells and patients' intolerance

Inactive Publication Date: 2011-03-23
SHANDONG HUAXIN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

While chemotherapy and radiotherapy kill cancer cells, they also damage normal tissue cells, and their severe adverse reactions make it difficult for patients to tolerate

Method used

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  • Medicinal composition with tumor inhibition function and preparation method and application thereof
  • Medicinal composition with tumor inhibition function and preparation method and application thereof
  • Medicinal composition with tumor inhibition function and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0126] Embodiment 1: the preparation of granule

[0127] Galangal 12kg Cyperus 6kg Pangosaurus 12kg

[0128] Extract volatile oil from galangal and Cyperus cyperi by steam distillation for later use, and filter the medicinal solution; reflux twice with 75% ethanol to recover ethanol, combine with the filtered medicinal liquid of galangal and Cyperus cyperi, dry, add excipients to granulate, and granulate , add the volatile oil extracted from galangal and Cyperus cyperi, and make granules according to the conventional method of pharmacy, 1 bag each time, 3 times a day.

Embodiment 2

[0129] Embodiment 2: the preparation of tablet

[0130] Galangal 6kg Cyperus 8kg Pangosaurus 6kg

[0131] Use steam distillation to extract volatile oil from galangal and Cyperus cyperi for later use, and filter the medicinal solution; reflux twice with 65% ethanol to recover ethanol, combine with the filtered medicinal liquid of galangal and Cyperus cyperi, dry, add excipients to granulate, and granulate , add the volatile oil extracted from galangal and Cyperus cyperi, and make tablets according to the conventional method of pharmacy, 4 tablets each time, 3 times a day.

Embodiment 3

[0132] Embodiment 3: the preparation of capsule

[0133] Galangal 29kg Cyperus 4kg Pangosaurus 29kg

[0134] Extract volatile oil from galangal and Cyperus cyperi by steam distillation for later use, and filter the medicinal solution; reflux twice with 85% ethanol to recover ethanol, combine with the filtered medicinal liquid of galangal and Cyperus cyperi, dry, add excipients to granulate, and granulate , add the volatile oil extracted from galangal and Cyperus cyperi, and make capsules according to the conventional method of pharmacy, 4 capsules each time, 3 times a day.

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Abstract

The invention discloses a drug composition with an effect of suppressing tumor, and discloses the process for preparing the drug composition and the purpose of the drug composition. The drug composition comprises three drugs such as galangal rhizome, nutgrass flatsedge rhizome and ningpo yam rhizome, and the steps of steam distillation, filtration, desiccation and the like are adopted in the preparation process. The drug composition of the invention comprises an alpinia-cyperus pill tinged with flavor, which is mainly used to treat stomach cancer, esophageal cancer and bowel malignant tumor. Experimental study shows that the drug composition of the invention also has a prominent effect in suppressing other tumors.

Description

technical field [0001] The invention relates to a pharmaceutical composition and a preparation method thereof, in particular to a pharmaceutical composition with tumor suppressing effect and a preparation method thereof. Background technique [0002] Although the morbidity and mortality of gastrointestinal malignant tumors, especially gastric cancer and esophageal cancer, continue to decline worldwide, they are still one of the most serious life-threatening malignant tumors in my country. There is still no effective treatment for patients with advanced gastric cancer, esophageal cancer and postoperative recurrence who have lost the opportunity for surgery. While chemotherapy and radiotherapy kill cancer cells, they also damage normal tissue cells, and their severe adverse reactions make it difficult for patients to tolerate. At present, research on anticancer drugs has gradually turned to natural plants and animals, focusing on discovering new anticancer ingredients or effe...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9062A61K9/08A61K9/10A61K9/16A61K9/20A61K9/48A61P35/00
Inventor 陈勃
Owner SHANDONG HUAXIN PHARMA
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