Method for preparing bolus for reinforcing middle-jiao and replenishing qi

A technology for Buzhong Yiqi pills and jujubes, applied in the directions of pill delivery, pharmaceutical formulations, and medical preparations containing active ingredients, etc., can solve the problems affecting product quality and curative effect, low qualification rate, long production cycle, etc. The effect of solving the uneven size of pellets, improving the yield of one-time finished products, and fast drug absorption

Inactive Publication Date: 2008-05-21
上海复星临西药业有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The whole process is complex, cumbersome, labor-intensive, difficult to operate, low pass rate of finished product, large difference in pellet weight, and long dissolution time
Usually, the labor intensity is high, the production cycle is long, the finished product rate is relatively low, and the size of the pills is uneven. Sometimes the dissolution time is too long and the drug cannot be absorbed, which not only brings inconvenience to the production, but also affects the product quality. and curative effect

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Sunburn Astragalus 200g, Codonopsis 60g, Zhilicorice 100g, Atractylodes macrocephala (fried) 60g, Angelica 60g, Cimicifuga 60g, Bupleurum 60g, tangerine peel 60g, a total of eight Chinese medicinal materials, and take 20g ginger and 40g jujube for later use;

[0019] Grind the Bawei Chinese herbal medicine into 80-mesh fine powder, mix well, and set aside;

[0020] Add 240g of water to decoct ginger and jujube for 0.5 hours, take the decoction liquid, add the above-mentioned fine powder, make granules, dry at 80°C, and granulate;

[0021] The granulated granules are added with 1% magnesium stearate by weight of the granules, and pressed into pellets with a die to obtain the final product.

[0022] The quality standards of Buzhong Yiqi Pills (water pills) recorded in "Chinese Pharmacopoeia" are used for detection. The comparison of some project indicators of Buzhong Yiqi Pills made by this method with the general method is shown in the following table:

[0023] ...

Embodiment 2

[0026] 200g sunburned astragalus, 60g codonopsis 60g, 100g roasted licorice, 60g Atractylodes macrocephala (stir-fried), 60g angelica, 60g cohosh, 60g bupleurum, 60g tangerine peel, a total of eight Chinese medicinal materials, and weigh 20g ginger and 40g jujube for later use;

[0027] Grind the Bawei Chinese medicinal materials into 200-mesh fine powder, mix well, and set aside;

[0028] Add 480g of water to decoct ginger and jujube for 1.5 hours, take the decoction liquid, add the above-mentioned fine powder, make granules, dry at 60°C, and granulate;

[0029] The sized granules are added with 0.2% silicon dioxide by weight of the granules, and pressed into pellets with a die to obtain the product.

[0030] The quality standards of Buzhong Yiqi Pills (water pills) recorded in "Chinese Pharmacopoeia" are used for detection. The comparison of some project indicators of Buzhong Yiqi Pills made by this method with the general method is shown in the following table:

[0031] ...

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PUM

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Abstract

The invention provides a method for preparing Buzhong Yiqi pill, comprising the steps as follows: the eight Chinese medical materials of broil radix astragali, radix codonopsitis, baked liquoric root, largehead atractylodesrhizome (fried), angelica, largetrifoliolious bugbane rhizome, bupleurum and tangerine peel are milled into fine powders respectively and then mixed evenly; an adhesive agent is added into the mixture to prepare gains; the grains are pressed into pills; and the adhesive agent is the boiling liquid of ginger and fructus zizyphi. The preparation method has the advantages of adopting a method of pressing preparation, simple technique, and easy operation. The product prepared with the method has stable quality, and the dissolving time of the product is shortened by over 70 to 95 percent when compared with the original Buzhong Yiqi pill, with quicker medicine absorption and higher content of astragaloside IV. The invention solves the problem of uneven size of bills preparing with the water pill method. Therefore, the dosage of the medicine can be more accurate, while the rate of finished products at one time can be increased.

Description

technical field [0001] The invention relates to a preparation method of Buzhong Yiqi Pill for treating diarrhea, prolapse of the anus, prolapse of the genitals, symptoms of body fatigue and weakness, abdominal distension due to lack of food, chronic stool diarrhea, anal prolapse or prolapse of the anus, and uterine prolapse. Background technique [0002] Buzhong Yiqi Pills are prepared from eight medicinal materials including Radix Astragali, Codonopsis Radix, Radix Glycyrrhizae, Atractylodes macrocephala (stir-fried), Angelica, Cimicifuga, Bupleurum, and Tangerine Peel. , used for diarrhea caused by weakness of the spleen and stomach, subsidence of Qi, prolapse of the anus, erection of the genitals. Symptoms include fatigue, lack of appetite, abdominal distension, prolonged stool diarrhea, anal prolapse or prolapse of the anus, and uterine prolapse. [0003] At present, Buzhong Yiqi pills are yellow-brown to brown water pills. Water pills are a traditional form of tradition...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61K9/20A61P1/12A61P1/14A61P15/00
Inventor 李德强张玉民陈卫东
Owner 上海复星临西药业有限公司
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