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Traditional Chinese medicine for treating hepatitis B and preparation method thereof

A technology of traditional Chinese medicine and hepatitis B, applied in the field of biopharmaceuticals, can solve the problems of high cost of long-term medication, difficulty in determining the course of treatment, and large adverse reactions, and achieve the effect of delaying and preventing further deterioration and less loss of active ingredients

Inactive Publication Date: 2009-03-25
KUNMING UNIV OF SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Currently used anti-hepatitis B virus drugs such as interferon have limited efficacy and relatively large adverse reactions; although nucleosides have strong and fast antiviral effects, the course of treatment is difficult to determine, and long-term drug treatment will produce drug resistance. Causes ALT and HBV DNA breakthrough (breakthrough), leading to disease progression
And the cost of long-term medication is high

Method used

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  • Traditional Chinese medicine for treating hepatitis B and preparation method thereof
  • Traditional Chinese medicine for treating hepatitis B and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] A. Take materials according to the following formula: Ganoderma lucidum 40g, Xihuangcao 30g, Zibei tooth 10g, Polygonum cuspidatum 8g, Hedyotis diffusa 12g;

[0043] B, through the following preparation process:

[0044] (1) Take the clean purple shellfish, put it in a refractory container, calcinate it on a smokeless furnace until the whole body is red, take it out, let it cool, and grind it into powder for later use.

[0045] (2) After mixing the Zibei tooth powder obtained in (1) with Ganoderma sinensis, Xihuangcao, and Hedyotis diffusa, add water to decoct twice, add 1200ml water for the first time; add the same 1200ml water for the second time, Decoct for 1.5 hours, filter, combine the filtrate, and concentrate the filtrate into an extract; add ethanol with a concentration of 95% to make the ethanol content of the entire solution system reach 80%, and let it stand overnight; extract the supernatant, and extract the precipitated extract spare;

[0046] (3) Add 48m...

Embodiment 2

[0049] A. Take materials according to the following formula: 50g of ganoderma lucidum, 20g of Xihuangcao, 15g of Zibei tooth, 5g of Polygonum cuspidatum, 10g of Hedyotis diffusa;

[0050] B, through the following preparation process:

[0051] (1) Take the clean purple shellfish, put it in a refractory container, calcinate it on a smokeless furnace until the whole body is red, take it out, let it cool, and grind it into powder for later use;

[0052] (2) Add water to the Zibei tooth powder obtained in (1), Ganoderma lucidum, Xihuangcao, and Hedyotis diffusa and decoct twice, add 1000ml of water for the first time; add 1000ml of water for the second time, decoct for 2 hours each time, Filtrate, combine the filtrates, concentrate the filtrates into extracts; add ethanol with a concentration of 95% to make the ethanol content of the entire solution system reach 70%, leave it to stand overnight, extract the supernatant, and deposit the extracts for subsequent use;

[0053] (3) Add...

Embodiment 3

[0056] A. Take materials according to the following formula: 20g Ganoderma lucidum, 40g Xihuangcao, 7g Zibeitooth, 20g Polygonum cuspidatum, 13g Hedyotis diffusa;

[0057] B, through the following preparation process:

[0058] (1) Take the clean purple shellfish, put it in a refractory container, calcinate it on a smokeless furnace until the whole body is red, take it out, let it cool, and grind it into powder for later use;

[0059] (2) Decoct the powder obtained in (1) with Ganoderma sinensis, Hedyotis diffusa, and Hedyotis diffusa with water twice, adding 15 times the amount of water for the first time. Add 15 times the amount of water for the second time, decoct for 1 hour each time, filter, combine the filtrate, and concentrate the filtrate into a thick extract. Add 95% ethanol to make the ethanol content of the whole solution system 85%, and let stand overnight. Extract the supernatant, and the precipitated extract is set aside;

[0060] (3) Add 8 times the amount of ...

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Abstract

The invention provides a Chinese Traditional Medicine for treating hepatitis B, which is characterized in that the Chinese Traditional Medicine is composed of following raw materials by weight percentage: 20 to 60 percent of twig and leaf of bignose rhinacanthus, 20 to 45 percent of linearstripe rabdosia herb, 7 to 15 percent of concha mauritiae, 5 to 20 percent of rhiaoma polygoni cuspidati and 8 to 20 percent of spreading hedyotis herb. The Chinese Traditional Medicine has the functions of invigorating the liver and the kidney, removing heat and toxin from liver and calming liver and suppressing liver-yang; and can prevent the hepatitis B virus from replicating, alleviate the liver inflammation and necrosis, protect the liver cells from fibrosis, improve the liver regeneration, delay and resist the repeated attacks which may result in illness exacerbation by begetting hepatocirrhosis and liver cancer. By utilizing the unique composite theory, cure principle and reasonable prescription combination in the Chinese Traditional Medicine, the Chinese Traditional Medicine adopts the pure Chinese Traditional Medicine for oral usage to cure hepatitis B with security, simplicity and fine curative effect. The Chinese Traditional Medicine can be made into granular formulation, troche, capsule and oral liquid with convenient use. The preparing method of the Chinese Traditional Medicine is scientific and reasonable with less loss of effective component and high extracting ratio.

Description

technical field [0001] The invention relates to a traditional Chinese medicine for treating hepatitis B and belongs to the technical field of biopharmaceuticals. Background technique [0002] Hepatitis B virus (HBV) is one of the most common viral infections in humans. Some people cannot completely clear the virus after acute infection with HBV, forming chronic hepatitis B (CHB). According to the statistics of the World Health Organization, about 2 billion people in the world have been infected with HBV, of which 350 million people have developed into chronic hepatitis B virus infection, and about 500,000 to 1.2 million people die each year from liver failure and cirrhosis caused by the development of hepatitis B disease. And primary hepatocellular carcinoma (HCC), hepatitis B has become the tenth killer of human life. my country is a high-incidence area of ​​hepatitis B. According to preliminary statistics, there are 120 million HBV carriers in the country, and nearly 300,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/74A61P1/16A61P31/20A61K35/56A61K35/618
Inventor 钱韵旭
Owner KUNMING UNIV OF SCI & TECH
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