Terpyridyl complex two-photon material with cell development and preparation

A terpyridine, cell imaging technology, applied in the direction of zinc organic compounds, preparations for in vivo tests, pharmaceutical formulations, etc., to achieve the effects of easy availability of raw materials, high yield and strong penetration
CN101475581AInactive Publication Date: 2009-07-08ANHUI UNIVERSITY
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
ANHUI UNIVERSITY
Publication Date
2009-07-08
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention disclose a two photon absorption material capable of imaging alive cells, which is a terpyridine derivative Zn(II)S2 complex. The complex is a two photon absorption material having a property of two-photon fluorescence imaging of alive tissue cells, has the characteristics of large absorption area, low excitation energy, large wavelength, high penetrability, less light injuries, non-toxicity and the like and is suitable to be used for detecting alive cells.
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Description

1. Technical field:

[0001] The invention relates to a two-photon absorption material and a preparation method thereof, in particular to a two-photon absorption material with the function of developing living tissue cells and a synthesis method thereof. 2. Background technology

[0002] In recent years, with the discovery of two-photon absorbing materials, two-photon fluorescence technology has made a major breakthrough in its application. Since the two-photon technology uses long-wavelength excitation (near-infrared), it has the characteristics of low excitation energy, long wavelength, strong penetration, and small photodamage. It has attractive application prospects in medical diagnosis and fluorescence microscopy imaging. In 2004, O'Halloran (J.Am.Chem.Soc., 2004, 126, 712-713) reported the use of Zn(II) ion-centered complex two-photon fluorescence microscopy in the detection of living tissue cells The application of this method has successfully solved the disadvantage o...

Claims

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