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Medicament for preventing and curing thrombus and preparation method thereof

A drug and thrombus technology, which is applied in the field of drugs for the prevention and treatment of thrombosis and its preparation, can solve the problems of low success rate and high cost, and achieve the effects of easy portability, high drug efficacy, and improvement of blood hypercoagulability

Inactive Publication Date: 2009-09-30
宋秋兰
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the former is expensive and the latter has a low success rate.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0051] Weigh 10 kg of the above-mentioned earthworm fibrinolytic enzyme, 15 kg of the above-mentioned Ganoderma lucidum polysaccharide, 10 kg of Danshen, 1 kg of Radix Astragali, and 1 kg of Ophiopogon japonicus.

[0052] Preparation method: (1) Select Salvia miltiorrhiza, extract with ethanol under reflux, collect the ethanol extract, filter, recover ethanol and concentrate it into an extract, wrap it with β-cyclodextrin, dry it for later use; evaporate the dregs of the medicine to remove the ethanol, and store it for later use .

[0053] (2) Select Radix Ophiopogon japonicus, extract with ethanol reflux, collect the ethanol extract, filter, recover ethanol and concentrate it into an extract, wrap it with β-cyclodextrin, and dry it for later use; the dregs of the medicine are evaporated to the ethanol and stored for later use.

[0054] (3) Take Radix Astragali, Salvia Miltiorrhiza and Ophiopogon japonicus dregs, decoct and extract, make extract, dry to obtain dry paste.

[005...

Embodiment 2

[0057] Weigh 25kg of the above-mentioned earthworm fibrinolytic enzyme, 10kg of the above-mentioned Ganoderma lucidum polysaccharide, 10kg of Danshen, 5kg of Radix Astragali, and 5kg of Ophiopogon japonicus.

[0058] Preparation method: (1) Select Salvia miltiorrhiza, extract with ethanol under reflux, collect the ethanol extract, filter, recover ethanol and concentrate it into an extract, wrap it with β-cyclodextrin, dry it for later use; evaporate the dregs of the medicine to remove the ethanol, and store it for later use .

[0059] (2) Select Radix Ophiopogon japonicus, extract with ethanol reflux, collect the ethanol extract, filter, recover ethanol and concentrate it into an extract, wrap it with β-cyclodextrin, and dry it for later use; the dregs of the medicine are evaporated to the ethanol and stored for later use.

[0060] (3) Take Radix Astragali, Salvia Miltiorrhiza and Ophiopogon japonicus dregs, decoct and extract, make extract, dry to obtain dry paste.

[0061] ...

Embodiment 3

[0063] Weigh 15kg of the above-mentioned earthworm fibrinolytic enzyme, 5kg of the above-mentioned ganoderma lucidum polysaccharide, 8kg of salvia miltiorrhiza, 2.5kg of astragalus, and 2.5kg of Ophiopogon japonicus

[0064] Preparation method: (1) Select Salvia miltiorrhiza, extract with ethanol under reflux, collect the ethanol extract, filter, recover ethanol and concentrate it into an extract, wrap it with β-cyclodextrin, dry it for later use; evaporate the dregs of the medicine to remove the ethanol, and store it for later use .

[0065] (2) Select Radix Ophiopogon japonicus, extract with ethanol reflux, collect the ethanol extract, filter, recover ethanol and concentrate it into an extract, wrap it with β-cyclodextrin, and dry it for later use; the dregs of the medicine are evaporated to the ethanol and stored for later use.

[0066] (3) Take Radix Astragali, Salvia Miltiorrhiza and Ophiopogon japonicus dregs, decoct and extract, make extract, dry to obtain dry paste.

...

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Abstract

The invention relates to a medicament for preventing and curing thrombus and a preparation method thereof. The medicament comprises the following components according to the weight portion: 10-25 of earthworm fibrinolysin, 5-15 of ganoderan, 5-10 of salvia miltiorrhiza, 1-5 of radix astraquli and 1-5 of ophiopogon root. The selected raw materials are respectively prepared and treated according to different characteristics, a proper amount of accessories are added after the obtained powders, extracting solutions and the like are mixed, and granular formulation, capsule, tablet, medicinal granules, and the like are respectively prepared by adopting different procedures. The invention is prepared by such raw materials as natural animal plant medicinal materials and cures the thrombus by the comprehensive function of various traditional Chinese medicine components; in addition, acute toxicology and long-time toxicology tests prove that the medicine has no harm to a human body, has high medicine effect, can improve the blood hypercoagulative state and the blood-fat, lower the blood sugar, dissolve the thrombus, dredge the microcirculation and increase the immunity.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a medicine for preventing and treating thrombosis and a preparation method thereof. Background technique [0002] Thrombosis is a common and frequently-occurring disease that seriously endangers human health. It is the culprit of cardiovascular and cerebrovascular diseases. Cardiovascular diseases in the world kill 12.5 million people every year. In my country, there are 3 million new such patients every year. Only 4%. The etiology is that the coagulation system and fibrinolytic system in the body are in an uncoordinated state, and the amount of active plasminase is not enough to decompose fibrin, the main component of thrombus, leading to thrombosis, acute myocardial infarction and other cardiovascular and cerebrovascular diseases. At present, the drugs for treating thrombosis are mostly blood vessel dilating and thrombolytic drugs. However, the former is expensive a...

Claims

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Application Information

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IPC IPC(8): A61K38/49A61K9/16A61K9/20A61K9/48A61P7/02A61K31/715A61K36/8968
Inventor 宋秋兰
Owner 宋秋兰
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