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Botulinus toxin composition and preparation method thereof

A botulinum toxin and composition technology, applied in the field of botulinum toxin composition, can solve problems such as failure and limited effect

Inactive Publication Date: 2009-10-14
叶健
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0013] Hand and foot hyperhidrosis is a hereditary phenomenon of excessive sweating of the hands, feet or forehead due to overactive sympathetic nerves. The current treatment methods for this type of disease are mainly limited to topical aluminum chloride salts (aluminum chloride salts), glutaraldehyde surgical treatments such as topical antiperspirants, underarm skin excision, and thoracic sympathectomy; these treatments have limited efficacy and often fail

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  • Botulinus toxin composition and preparation method thereof

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Embodiment approach

[0029] Botox A per 100 units, dissolved in 1--10 milliliters (ML) of normal saline, and then mixed with 10--100CC blue gum to make a water-soluble colloid;

[0030] Botox A is dissolved in 1--10 milliliters (ML) of normal saline per 100 units, and then mixed with Theraplex (Vaseline water) to make a mixed cream;

[0031] Botox A per 100 units, dissolved in 1--10 milliliters (ML) of physiological saline, for subcutaneous or intradermal injection.

[0032] Yet another embodiment of the present invention

[0033] For every 100 units of Botox A, dissolve in 3--7 milliliters (ML) of normal saline, and then mix with 30--70CC blue gum to make a water-soluble colloid;

[0034] Botox A is dissolved in 3-7 milliliters (ML) of normal saline per 100 units, and then mixed with Theraplex (Vaseline water) to make a mixed cream;

[0035] Botox A per 100 units, dissolved in 3--7 milliliters (ML) of normal saline, for subcutaneous or intradermal injection.

[0036] Yet another embodiment of ...

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Abstract

The invention relates to a botulinus toxin composition used for inhabiting the medium transfer of teleneuron so as to inhabit the over-secretion of skin glands and treat or prevent diseases of skin gland function over-strengthening. The botulinus toxin composition is used for treating diseases of whelk (common acne), folliculitis, rosacea, seborrheic dermatitis, armpit odor, palm and foot hyperhidrosis, and the like and the over-secretion diseases of the skin glands. A method for treating the diseases is to use hypodermic injection or surface local smearing. It is believed that gland secretion is inhabited mainly by the function of sympathetic and parasympathetic preganglionic endings, thereby achieving the effects on diminishing inflammation and removing sweat and odor, and the treating method is commonly used every three months.

Description

technical field [0001] The present invention relates to a composition of botulinum toxin for inhibiting the transmission of nerve terminal mediators and thereby inhibiting the excessive secretion of skin glands, so as to treat or prevent diseases with excessively enhanced functions of skin glands. Background technique [0002] Botulinum toxin is a kind of neuroexotoxin, which is secreted by anaerobic Gram-negative bacilli (Clostridium botulinum). May get a disease called botulism (botulism), the main clinical manifestation is muscle weakness, in more serious cases, may even die due to paralysis of respiratory muscles, the toxin secreted by botulism, a species There are seven types of toxins including A, B, C1, D, E, F, and G. These toxins have a strong nerve paralysis effect. When the botulinum toxin acts, the potential signal of the nerve cannot be transmitted to the muscle, resulting in the inability of the muscle to contract. Paralysis, acting on the choline nerve termin...

Claims

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Application Information

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IPC IPC(8): A61K35/74A61K38/48A61K9/00A61K9/107A61P17/00A61P17/10
Inventor 叶健
Owner 叶健
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