The invention provides a targeted antiperspirant, and relates to the technical field of targeted
antiperspirants. The preparation method of the targeted antiperspirant specifically comprises the following steps: (1) preparing a chelating protective agent; (2) preparing an
aluminum chlorohydrate activating solution; (3) preparing blank micelles; (4)
micelle loading; (5) cooling and curing; and (6) emulsification preparation. According to the technology, the self-
assembly characteristic of
poloxamer 407 is utilized, micelles with the particle size of about 20nm are formed through self-
assembly, the micelles are disintegrated at the
skin temperature and release
aluminum chlorohydrate nanogel clusters through
nucleation and efficient
entrapment of
aluminum chlorohydrate hydrolysis intermediates, the micelles are crosslinked into a porous physical membrane after encountering sweat,
sweat gland ducts are reversibly blocked, and the effect of inhibiting the
sweat gland ducts is achieved. According to the present invention, with the application of the
bisabolol, the sweat can be prevented from being smoothly discharged to the
skin surface so as to achieve the efficient sweat stopping effect, the
inulin and the antibacterial component are added to maintain the balance of the armpit
flora, the sweat stopping and the deodorization are combined, and the
bisabolol can be efficiently fused so as to relieve the
skin and strengthen the
skin barrier during the
nursing.