Application of traditional Chinese medicine composition in preparing medicament for curing senile dementia

A technology for senile dementia and composition, which is applied in the direction of drug combination, active ingredients of hydroxyl compounds, medical raw materials derived from arthropods, etc., and can solve problems such as the application of undisclosed traditional Chinese medicine compositions

Active Publication Date: 2009-10-21
HEBEI YILING MEDICINE INST
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

The above two patents do not disclose the application of the traditional Chinese medicine composition in the preparation of drugs for the treatment of senile dementia

Method used

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  • Application of traditional Chinese medicine composition in preparing medicament for curing senile dementia
  • Application of traditional Chinese medicine composition in preparing medicament for curing senile dementia
  • Application of traditional Chinese medicine composition in preparing medicament for curing senile dementia

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] a) The raw material drug formula is:

[0043] Ginseng 39.6g Leech 72.6g Wood Beetle 46.2g Frankincense (made) 13.2g

[0044] Paeoniae Rubra 33g Dalbergia 13.2g Sandalwood 13.2g Scorpio 19.8g

[0045] Cicada slough 46.2g centipede 6.6g borneol 33g Suanzaoren (stir-fried) 33g;

[0046] b) Crushing process of medicinal materials:

[0047] The scorpion, leech, centipede, ground beetle, and cicada slough five kinds of insect medicines have been cleaned, washed and processed, and the frankincense prepared after cleaning is prepared according to the prescription, and crushed by a pulverizer, and the fineness of the powder reaches more than 80 mesh; The powdered medicine is ultrafinely pulverized by various ultrafine pulverization techniques, so that the average particle size of the medicine powder is less than 30-40 μm; the medicinal materials to be pulverized are washed, dried and sterilized, and the ingredients are prepared;

[0048] c) Extraction concentration and drying...

experiment example 1

[0064] 1 Materials and methods

[0065] 1.1 Test drug:

[0066] The medicine superfine powder capsule of the present invention: prepare according to the formula of raw material drug and preparation process of embodiment 1.

[0067] Common powder capsule of the medicine of the present invention: prepared according to the raw material medicine formula and preparation process of the comparative example.

[0068] 1.2 General Information All cases were selected from patients in Hebei Yiling Hospital from May 2004 to December 2007. A total of 96 cases were mild to moderate patients with a score of 10-24 on the Mini-Mental State Examination (MMSE), and the course of disease was 0.5 - Between 3 years, with an average of 2 years. The patients were randomly divided into three groups: the common powder capsule group of the present invention, the superfine powder capsule of the present invention and a control group. 30 examples of the medicine common powder capsule group of the present...

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Abstract

The invention discloses an application of traditional Chinese medicine composition in preparing medicament for curing senile dementia. The traditional Chinese medicine composition mainly contains ginseng, leech, scorpion, woodlouse, chilopod, cicada ecdysis, red paeonia, sandalwood, dalbergia wood, frankincense, wild jujube and borneol and is prepared perfectly by modern pharmaceutical technique. Clinical tests prove that the traditional Chinese medicine composition can effectively cure senile dementia including Alzheimer dementia, dementia caused by vascular disease and mixed dementia.

Description

technical field [0001] The invention relates to a new application of a traditional Chinese medicine composition. Specifically, the present invention relates to an application of a traditional Chinese medicine composition in preparing medicine for treating senile dementia, which belongs to the field of traditional Chinese medicine application. Background technique [0002] Dementia syndrome (dementia syndrome) is a chronic and comprehensive mental disorder, with slowly appearing mental decline as the main clinical feature, including the decline of memory, thinking, understanding, judgment, calculation and other functions and varying degrees of personality changes. Usually there is no disturbance of consciousness. Dementia can occur in people of all ages, but is most common in the elderly. [Chen Haozhu. Practical Internal Medicine. People's Health Publishing House, 2005, 2751-2752.] Its exact cause is unknown, but it is related to genetics and neuron degeneration. The main p...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/725A61K9/20A61K9/48A61K9/10A61K9/16A61K9/14A61P25/28A61K31/045A61K35/64A61K35/62A61K35/646A61K35/648
Inventor 吴以岭
Owner HEBEI YILING MEDICINE INST
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