Traditional Chinese medicine ophthalmic preparation and preparation method thereof

A technology of ophthalmic preparations and traditional Chinese medicines, which is applied in the direction of pharmaceutical formulas, medical preparations containing non-active ingredients, medical preparations containing active ingredients, etc., which can solve the problem of slow dissolution rate and release speed of active ingredients and the inability to ensure that the drugs are fully mixed and uniform , Low bioavailability of active ingredients and other issues, to achieve the effect of improving bioavailability, low energy utilization rate, and small particle size distribution range

Inactive Publication Date: 2009-11-18
BEIJING HERUN INNOVATION PHARMA TECH DEV
View PDF0 Cites 9 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, the preparation process of the above-mentioned traditional Chinese medicine ophthalmic preparations is mostly pulverized first, and then combined with the traditional compounding method to prepare powder or ointment. There are certain defects in the preparation process: ① the traditional compounding method cannot ensure that the medicine is fully mixed; The production efficiency of the compounding research method is low, the production cycle is long, and the production cost is correspondingly increased; ③The particle size of the fine powder of the drug after crushing is relatively l

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Embodiment 1 (prescription is derived from Zijinding eye drops)

[0027] Prescription: calamine (calcined) 140g borneol 80g gypsum (calcined) 200g

[0028] Daqing Salt 10g Borax 10g

[0029] Preparation method: take the above five flavors, take calamine (calcined) and gypsum (calcined) and coarsely pulverize them, put them in a vibrating ultrafine pulverizer for 15 minutes, then add three flavors such as borneol, continue to pulverize them for 55 minutes, and discharge , to prepare Zijinding Eye Powder.

Embodiment 2

[0030]Example 2 (the prescription comes from Bai Jingyu eye medicine)

[0031] Prescription: Stone Cassia (calcined) 100g, bear bile 20g, pearl (tofu broiled) 5g

[0032] Seaweed octopus 94.5g Calamine (calcined Coptis chinensis) 165g Naked sand (burnt) 0.6g

[0033] Musk 2.5g Borneol 162g

[0034] Preparation method: Take the above eight flavors, take cassia (calcined), octopus, calamine and borneol, and coarsely grind them, put them in a vibrating ultrafine pulverizer for ultrafine grinding for 10 minutes, then add four flavors such as bear bile, and continue to grind Pulverize for 60 minutes to obtain ultrafine drug powder, and set aside; take another 380g of Vaseline and an appropriate amount of liquid paraffin, heat at 150°C for 1 hour, filter, let cool to 55°C, add the above ultrafine drug powder, mix well, and obtain Bai Jingyu eye ointment.

Embodiment 3

[0035] Embodiment 3 (prescription is derived from Poyunsan eye drops)

[0036] Prescription: Bezoar 5g, musk 5g, borneol 4.68g

[0037] Cinnabar 16g Amber 24g Nauma 4.8g

[0038] Borax 48g Calamine (calcined) 625g

[0039] Preparation method: Take the above eight flavors, take cinnabar water and fly to very fine powder, dry naturally, pass through a 500-mesh sieve, and set aside; take calamine (calcined) and borax and put them in a vibrating ultrafine pulverizer for ultrafine grinding for 25 minutes, then Add the five flavors of bezoar and other five flavors, continue to ultrafinely pulverize for 25 minutes to obtain ultrafine drug powder, add the above-mentioned cinnabar ultrafine powder, mix well, and set aside; take another 20g of carbomer, add appropriate amount of water to swell for 24 hours, add triethanolamine to adjust When the pH reaches 8, add the above-mentioned ultrafine drug powder and 8 g of azone, stir evenly, add water to 2000 g, and stir evenly t...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
Granularityaaaaaaaaaa
D90aaaaaaaaaa
Login to view more

Abstract

The invention discloses a traditional Chinese medicine preparation, in particular a traditional Chinese medicine preparation for treating ophthalmic diseases and a preparation method thereof. The prepared preparation is powder, ointment or gelata and belongs to the field of traditional Chinese medicine. The preparation has the advantages that the prescription originates from a classic and famous transcription of the Drug Standard of Ministry of Public Health of the People's Republic of China, the preparation method induces an ultrafine grinding technology for the first time, the raw materials (especially minerals and animal medicines) have thorough grinding, small granularity and large specific area, active ingredients can be better exposed to be in a release condition, so the dissolution rate of the active ingredients is greatly enhanced, the biological availability is enhanced multiply and the general reaction of clinic curative effect is good; at the same time, the foreign body sensation is obviously relieved and granular sensation almost disappears when the preparation is used by a suffer, thereby the preparation is an ideal medicine for treating ophthalmic diseases, is deeply popularized with suffers and has wide market prospect.

Description

technical field [0001] The invention relates to a traditional Chinese medicine ophthalmic preparation, in particular to a traditional Chinese medicine ophthalmic preparation for treating ophthalmic diseases and a preparation method thereof. The prepared preparation is powder, ointment or gel, and belongs to the field of traditional Chinese medicine. Background technique [0002] Eyes are the windows of the soul, which shows how important it is to us. However, with the changes in people's living habits and the influence of the external environment in recent years, ophthalmic diseases have gradually become a frequently-occurring and common disease. Tears, photophobia and wind, eye itching, blurred vision, trachoma, cloudy eyes, cataract, conjunctivitis, stye, blepharitis, etc. have seriously affected people's normal work and life, and have attracted widespread attention from all walks of life. . [0003] There are many western medicines for the treatment of ophthalmic diseas...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61K36/00A61K9/14A61K9/06A61K9/00A61K47/38A61K47/44A61K47/32A61P27/02A61P27/12A61K33/30A61K35/56A61K35/55A61K36/758A61K36/89A61K36/718A61K36/88A61K35/413A61K36/906A61K36/8984A61K36/515A61K47/06
CPCY02A50/30
Inventor 王广录柴金苗
Owner BEIJING HERUN INNOVATION PHARMA TECH DEV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap