Compound ofloxacin injection for animals for treating postnatal infection and preparation method thereof
A compound ofloxacin, postpartum infection technology, applied in the directions of medical preparations containing active ingredients, devices for making medicines into special physical or taking forms, pharmaceutical formulas, etc. , treatment of inconvenience and other problems, to achieve the effect of treating indigestion, speeding up postpartum recovery, and promoting gastrointestinal motility
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Embodiment 1
[0022] (1) Weigh 0.5 kg ofloxacin and put it into 25 L of water for injection, then add 1000 ml of hydrochloric acid with a volume percentage concentration of 37.5%, and stir until completely dissolved.
[0023] (2) Put 15 billion units of kanamycin sulfate into 50 L of water for injection at about 80°C, and stir until completely dissolved.
[0024] (3) Take 5 L of water for injection, dissolve 0.1 kg of bethanechol ammonium chloride, and 0.06 kg of dexamethasone sodium phosphate.
[0025] (4) Combine the solutions prepared in step (1), step (2) and step (3), then add water for injection to 100L, stir evenly, keep for 15-20min, use a volume percentage concentration of 20% hydrochloric acid solution or mass The sodium hydroxide solution with a percentage concentration of 40% is used to adjust the pH value to 4.22, and the compound ofloxacin injection for veterinary treatment of postpartum infection of the present invention is prepared after the liquid is clarified.
Embodiment 2
[0027] (1) Weigh 10 kg ofloxacin and put it into 25 L of water for injection, then add 1000 ml of hydrochloric acid with a volume percentage concentration of 37.5%, and stir until completely dissolved.
[0028] (2) Put 3 billion units of kanamycin sulfate into 50 L of water for injection at about 80°C, and stir until completely dissolved.
[0029] (3) Take 5 L of water for injection, dissolve 0.02 kg of bethanechol ammonium chloride, and 0.06 kg of dexamethasone sodium phosphate.
[0030] (4) Combine the solutions prepared in step (1), step (2) and step (3), then add water for injection to 100L, stir evenly, keep for 15-20min, use a volume percentage concentration of 20% hydrochloric acid solution or mass The sodium hydroxide solution with a percentage concentration of 40% adjusts the pH value to 4.15, and the compound ofloxacin injection for veterinary treatment of postpartum infection of the present invention is prepared after the liquid is clarified.
Embodiment 3
[0032] (1) Weigh 1 kg ofloxacin and put it into 25 L of water for injection, then add 1000 ml of hydrochloric acid with a volume percentage concentration of 37.5%, and stir until completely dissolved.
[0033] (2) Put 10 billion units of kanamycin sulfate into 50 L of water for injection at about 80°C, and stir until completely dissolved.
[0034] (3) Take 5 L of water for injection, dissolve 0.08 kg of bethanechol ammonium chloride, and 0.06 kg of dexamethasone sodium phosphate.
[0035] (4) Combine the solutions prepared in step (1), step (2) and step (3), then add water for injection to 100L, stir evenly, keep for 15-20min, use a volume percentage concentration of 20% hydrochloric acid solution or mass The sodium hydroxide solution with a percentage concentration of 40% adjusts the pH value to 4.33, and the compound ofloxacin injection for veterinary treatment of postpartum infection of the present invention is prepared after the liquid is clarified.
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