Eriosema chinense isoflavoid compound and extraction method and application thereof

Abstract

The invention discloses an eriosema chinense isoflavoid compound and an extraction method and applications thereof. The eriosema chinense isoflavoid compound is a white raphide isoflavoid compound, and the extraction method thereof comprises the following steps: grinding eriosema chinense root tubers, carrying out backflow extraction and reduced pressure concentration by alcohol to obtain extractum, extracting the injectable suspension prepared by adding water into the extractum through petroleum ether, carrying out extraction on the left injectable suspension after being extracted by petroleum ether by ethylacetate and performing reduced pressure on the extract to obtain ethylacetate extractum; dissolving the ethylacetate extractum by the bottom face of a solvent system mixed by normal hexane: ethylacetate: methanol: water; extracting the solvent liquid with equivoluminal top phase for multiple times until the top phase is colorless; drying the bottom phase partly to obtain ethylacetate extractum II; separating the ethylacetate extractum II by preparative HSCCC; manually collecting the constituent eluate with symmetrical peeks and high content; and evaporating part solvent of theeluate to obtain the isoflavoid compound which has the bacteria-resistant, anti-inflammatory, cough-relieving and sputum-resolving functions.

Description

Technical field: [0001] The invention relates to an extraction method and application of piglet isoflavone compounds, belonging to the field of medicine. Background technique: [0002] The genus Eriosema chinense Vog is a plant of the genus Fabaceae, about 100 species, distributed in tropical and subtropical regions. According to the "Dictionary of Chinese Medicine", the roots of piglets are used as medicine, which has the effects of clearing away heat and detoxification, generating heat and polydipsia, reducing phlegm and moisturizing the lungs, and relieving cough. Rare and valuable Chinese herbal medicine for injuries and other diseases. Zhuzai Li is mainly used to treat cough and asthma. It has remarkable curative effect, is safe and reliable, cheap and convenient. It is a good resource of Chinese herbal medicine and is worthy of development, research and popularization. Although Zhuzai Li has been widely used among the people, there are no relevant literature reports ...

AI Technical Summary

Problems solved by technology

Although Zhuzai Li has been widely used among the people, there are no relevant literature reports on the active ingredients and biological activities of Zhuzai Li, and the clinical mechanism of Zhuzai Li is not yet clear. The range of clinical application has not been fully and effectively developed and utilized

At the same time, due to the unknown main active ingredients, it is impossible to detect the active ingredients of Zhuzai Li, effectively control the quality of medicinal materials, and conduct authoritative identification of authentic medicinal materials

[0003] Among the many studies of traditional Chinese medicine, there are few studies on active ingredients, pharmacological effects, and the relationship between drug efficacy and ingredients, so it is impossible to clarify the material basis of Chinese medicine efficacy in treating diseases and mechanism of action and other important scientific issues, nor can it provide a lead or structural core for finding new drugs or synthesizing new drugs, and cannot improve the research methods and technical level of new Chinese medicines

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