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Application of loop proline-leucine in preventing and removing marine fouling organisms

A cycloproline and marine fouling technology, applied in the field of marine antifouling coatings, has achieved good application prospects, easy access, and great potential for popularization and application

Active Publication Date: 2012-09-05
SOUTH CHINA SEA INST OF OCEANOLOGY - CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But at present, in the field of marine antifouling, there is no relevant report disclosing the role of cyclic dipeptides in biofouling control

Method used

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  • Application of loop proline-leucine in preventing and removing marine fouling organisms
  • Application of loop proline-leucine in preventing and removing marine fouling organisms

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Experimental group I: cycloproline-leucine was dissolved in methanol to prepare a solution with a concentration of 28.26 μg / ml. Add 1 ml of this solution to a petri dish with a diameter of 6 cm, and make it evenly cover the bottom of the petri dish. After the solvent is completely evaporated, the content of cycloproline-leucine coated on the bottom of the culture dish is 1 μg / cm 2 . Add 10ml of seawater.

[0029] Experimental group II: Cycloproline-leucine was dissolved in methanol to prepare a solution with a concentration of 1851.03 μg / ml. Add 1 ml of this solution to a petri dish with a diameter of 6 cm, and make it evenly cover the bottom of the petri dish. After the solvent is completely evaporated, the content of cycloproline-leucine coated on the bottom of the culture dish is 65.5 μg / cm 2 . Add 10ml of seawater.

[0030] Control group: Add 1ml of methanol to distribute the solution evenly on the bottom of the petri dish, and then add 10ml of seawater after th...

Embodiment 2

[0037] Experimental group: cycloproline-leucine was dissolved in methanol to prepare a solution with a concentration of 282.6 μg / ml. Add 1 ml of this solution to a petri dish with a diameter of 6 cm, and make it evenly cover the bottom of the petri dish. After the solvent is completely evaporated, the content of cycloproline-leucine coated on the bottom of the culture dish is 10 μg / cm 2 . Add 10ml of seawater.

[0038] Control group: Add 1ml of methanol to distribute the solution evenly on the bottom of the petri dish, and then add 10ml of seawater after the solvent has evaporated completely.

[0039] Blank group: add 10ml of seawater.

[0040] Determination of the number of larvae: Take the water body containing the larvae of Pinctada martensii from the nursery pond and concentrate it with a sieve. Take 50ml each for three times, add 1-2 drops of formalin solution to kill the larvae, and then count them under a microscope. The average value obtained is the density of larv...

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Abstract

The invention discloses application of loop proline-leucine in preventing and removing marine fouling organisms. The molecular formula of the loop proline-leucine is C11H18N202, and the molecular weight is 210. The loop proline-leucine has an obvious inhibition function on the attachment of marine organisms on solids, and meanwhile, the loop proline-leucine as a naturally existing organic compound can not pollute water environment, has safety and no toxicity, and can not kill the marine organisms when inhibiting the attachment of the marine organisms, and is different from most of existing anti-fouling substances extracted from the marine organisms. The invention has the advantages of mature artificial synthesizing technology, simple obtaining approach, reliable and stable source and favorable application prospect in preventing and removing fouling organisms of various marine artificial facilities, and is suitable for mass production.

Description

technical field [0001] The invention belongs to the field of marine antifouling coatings, and in particular relates to the application of a cyclic dipeptide in the prevention and control of marine fouling organisms. Background technique [0002] Marine fouling organisms refer to marine organisms that are fixed or inhabited on the underwater solid surface of ships and various artificial facilities, and have adverse effects on human economic activities. The main hazards are to increase the resistance of ships, reduce the speed of navigation, and increase fuel consumption; Blocking water pipes; changing metal corrosion process, resulting in localized corrosion or perforation; hindering the normal operation of various marine facilities, causing drift, imbalance or even overturning; in marine aquaculture, it will also compete with cultured shellfish for attachment base and bait, Hinder the growth and development of breeding objects, and reduce the quality of aquatic products. ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C09D5/16
Inventor 刘永宏严涛杨斌曹文浩杨献文
Owner SOUTH CHINA SEA INST OF OCEANOLOGY - CHINESE ACAD OF SCI
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