Structure of radioactive micro balls and preparation method

A radioactive and microbead technology, applied in the field of microbeads, can solve the problems of limited application range, large volume, radiation, etc., and achieve the effect of improving therapeutic benefit, promoting apoptosis, and reducing damage
CN101757644AInactive Publication Date: 2010-06-30李树义

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
李树义
Publication Date
2010-06-30
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to the structure of radioactive micro balls and a preparation method. At least one micro ball having isotopes which can radiate beta or gamma-ray is added in a biocompatible substance; and the biocompatible substance represents biological materials and chemical materials which can be used for the clinical cure: biologic glass, biologic ceramics, biologic resin and liposome, etc. The preparation method comprises the steps: 1. activation method: putting phosphorus or yttrium-containing into an irradiation container of an atom reacting device, and irradiating the micro balls with neutron, so that the phosphorus or the yttrium is activated to be radioactive phosphorus (32P) or radioactive yttrium (90Y); and 2. mixing method: mixing isotope (such as 125I and 103Pd) which has radiate beta or gamma- ray with entitative or hollow micro balls, carrying the isotopes into human bodies by taking the micro balls as the carrier of the isotope for the radiotherapy of tumor. The radioactive micro balls have the volume which is in the range of nanometer and micrometer, and can release beta or gamma ray; and the isotope is one or several, has short radiation range, reduces the side effects of the radiotherapy of the tumor, and can be induced into the human bodies by means of local intervention or surgery through blood vessels.
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Description

technical field

[0001] The present invention relates to a microbead for tumor and cancer treatment, in particular to a structure and a preparation method of a radioactive microsphere for tumor and cancer treatment. technical background

[0002] In recent years, radioactive seed (Radioactive seed) treatment of tumors has developed rapidly. Commonly used radioactive particles 125 Particle I is made of a titanium tube with a length of 4.5 millimeters (mm) and a diameter of 0.8 millimeters (mm). 125 I'm a silver rod. It can radiate gamma rays, and each particle contains a radiation dose of 0.4-1.0 mCi (average 0.6 mCi). The half-life is 59.4 days, and it takes 240 days to release 94% of the radiation dose. This new technology has been used in the treatment of prostate cancer, cervical cancer, osteosarcoma, head and neck tumors, pancreatic cancer, liver cancer, lung cancer, mediastinal tumors, etc. There are three implantation methods for radioactive seeds to treat tumors: 1....

Claims

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