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Whitening cosmetic product, preparation method and application thereof

A whitening cosmetic and a whitening technology are applied in the field of whitening cosmetic and its preparation, which can solve the problems such as the absorption and the shelf life need to be improved, and achieve the effect of good whitening effect.

Active Publication Date: 2010-09-01
广州泰润合投资有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, its active absorption and shelf life need to be improved

Method used

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  • Whitening cosmetic product, preparation method and application thereof
  • Whitening cosmetic product, preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Preparation of whitening freeze-dried powder:

[0035] Weigh 0.2g ANG-1, 0.2g metallothionein, 0.2g hEGF, 0.2g IL-1RA, 20g superoxide dismutase, 40g low molecular weight heparin sodium, 200g arbutin, 1000g stabilizer, add 20000ml injection grade water , after filtering and sterilizing, fill in 2.1ml / bottle, and use a vacuum freeze dryer to run for 20 to 40 hours.

[0036] The formula of the stabilizer is: mannitol and water with a concentration of about 4wt%; sodium vitamin C phosphate with a concentration of about 1wt%; and sorbic acid with a concentration of about 5mM.

[0037] Preparation of whitening base liquid:

[0038] Basic liquid formula: (wt%)

[0039] Hyaluronic Acid 0.1

[0040] Oat Beta-Raylan 2.0

[0041] Lactobacillus / mung bean fermentation broth 0.5

[0042] Lysoprotease 1.5

[0043] 1,2 Octanediol / Hexanediol 0.4

[0044] The remainder is water.

[0045] After the above formula is dissolved, it is sterilized by filtration, filled and capped at 3ml / ...

Embodiment 2

[0047] Preparation of whitening freeze-dried powder:

[0048] Weigh 0.4g ANG-1, 0.4g metallothionein, 0.2g hEGF, 0.2g IL-1RA, 40g superoxide dismutase, 40g low molecular weight heparin sodium, 400g arbutin, 1000g stabilizer, add 20000ml injection grade water , after filtering and sterilizing, fill in 2.1ml / bottle, and run for 20 to 30 hours in a vacuum freeze dryer.

[0049] Wherein the stabilizer formula is: glycine with a concentration of about 1wt%, mannitol and water with a concentration of 4wt%; vitamin E with a concentration of about 1wt%; phosphoric acid with a concentration of about 5mM;

[0050] Preparation of whitening base liquid:

[0051] Basic liquid formula: (wt%)

[0052] Hyaluronic Acid 0.05

[0053] Oat Beta-Raylan 2.0

[0054] Methylpropanediol 3.0

[0055] Lactobacillus / mung bean fermentation broth 0.5

[0056] Sodium Vitamin Phosphate 3.0

[0057] 1,2 Octanediol / Hexanediol 0.4

[0058] The remainder is water.

[0059] After the above formula is dis...

Embodiment 3

[0061] Preparation of whitening freeze-dried powder:

[0062] Add 0.6g ANG-1, 0.2g metallothionein, 0.4g hEGF, 0.4g IL-1RA, 20g superoxide dismutase, 40g low molecular weight heparin sodium, 400g arbutin, 1200g stabilizer, add 20000ml injection grade water, After filtering and sterilizing, it is filled with 2.1ml / bottle, and it is operated in a vacuum freeze dryer for 20 to 30 hours.

[0063] Wherein the stabilizer formula is: trehalose with a concentration of about 1.5wt%, mannitol and water with a concentration of 4.5wt%; protein hydrolyzate with a concentration of about 1wt%; glycine with a concentration of about 5mM;

[0064] Preparation of whitening base liquid:

[0065] Basic liquid formula: (wt%)

[0066] Hyaluronic Acid 0.5

[0067] Oat Beta-Raylan 2.0

[0068] Lactobacillus / mung bean fermentation broth 0.5

[0069] Soy Isoflavones 3.0

[0070] 1,2 Octanediol / Hexanediol 0.4

[0071] The remainder is water.

[0072] After the above formula is dissolved, it is st...

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PUM

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Abstract

The invention discloses a whitening cosmetic product, a preparation method and application thereof. The whitening cosmetic product comprises the components in percentage by mass: 0.00001to 0.001 percent of recombined human angiogenin, 0.00001 to 0.001 percent of metallothionein, 0.00001 to 0.001 percent of human epidermal growth factor, 0.00001to 0.001 percent of IL-1RA, 0.1 to 0.5 percent of superoxide dismutase, 0.1 to 0.5 percent of low molecular liquaemin, 1 to 5 percent of arbutin, 5 to 25 percent of stabilizer, 0.02 to 0.3 percent of hyaluronic acid, 0.5 to 5 percent of methylpropanediol, 0.5 to 3.5 percent of lactobacillus / mung bean fermentation liquid, 0.5 to 5 percent of dissolved protease, 0.5 to 8 percent of vitamin C sodium phosphate, 0.3 to 0.7 percent of 1,2-hexanediol or 1,2-capryl glycol, 1 percent to 5 percent of oat Beta-glucan, 1 to 5 percent of soy isoflavone and the balance of water. The whitening cosmetic product can be preserved for a long time, has no side effect on skin and is suitable for long term use.

Description

technical field [0001] The invention relates to the field of cosmetics, in particular to a whitening cosmetic and its preparation method and application. Background technique [0002] At present, the functional raw materials added to whitening cosmetics on the market mainly include one or more of arbutin, hydroquinone, kojic acid, mercury compounds, fruit acid, vitamin A acid, hormones, cell growth factors, etc. Some of the whitening cosmetics containing the above-mentioned raw materials have whitening effect and have certain side effects on the skin, while some have short-term efficacy after adding safe and no side effect raw materials, so they cannot be stored for a long time. If arbutin is highly photosensitive, a large amount of sunscreen should be added to the product, which will cause skin aging; hydroquinone can easily cause local skin redness or systemic side effects, and easily cause skin cancer; Stable and easy to change color, a large amount of antioxidants and u...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/73A61K8/66A61K8/64A61K8/60A61K8/99A61K8/67A61Q19/02A61Q19/08
Inventor 刘宪万宇
Owner 广州泰润合投资有限公司
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